Evidence map›Paper›PMID 34139191›Full record

ArticleCurrent biology : CB2021

Twitches emerge postnatally during quiet sleep in human infants and are synchronized with sleep spindles.

Greta Sokoloff, James C Dooley, Ryan M Glanz, Rebecca Y Wen, Meredith M Hickerson, Laura G Evans, Haley M Laughlin, Keith S Apfelbaum, Mark S Blumberg

Open access · bronzeAbstract read
In one paragraph

Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 48 citations in OpenAlex.

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  15. REM refines and rescues memory representations: a new theory.Sleep advances : a journal of the Sleep Research Society · 2025
    Review
  16. The effect of group size on sleep in a neotropical bat, Artibeus jamaicensis.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2024
    Article
  17. The importance of sleep for the developing brain.Current sleep medicine reports · 2024
    Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Greta SokoloffDepartment of Psychological and Brain Sciences, University of Iowa, 340 Iowa Avenue, Iowa City, IA 52242, USA; Iowa Neuroscience Institute, University of Iowa, Iowa City, IA 52242, USA. Electronic address: greta-sokoloff@uiowa.edu.
James C DooleyDepartment of Psychological and Brain Sciences, University of Iowa, 340 Iowa Avenue, Iowa City, IA 52242, USA.
Ryan M GlanzDepartment of Psychological and Brain Sciences, University of Iowa, 340 Iowa Avenue, Iowa City, IA 52242, USA.
Rebecca Y WenDepartment of Psychological and Brain Sciences, University of Iowa, 340 Iowa Avenue, Iowa City, IA 52242, USA.
Meredith M HickersonDepartment of Psychological and Brain Sciences, University of Iowa, 340 Iowa Avenue, Iowa City, IA 52242, USA.
Laura G EvansDepartment of Psychological and Brain Sciences, University of Iowa, 340 Iowa Avenue, Iowa City, IA 52242, USA.
Haley M LaughlinDepartment of Psychological and Brain Sciences, University of Iowa, 340 Iowa Avenue, Iowa City, IA 52242, USA.
Keith S ApfelbaumDepartment of Psychological and Brain Sciences, University of Iowa, 340 Iowa Avenue, Iowa City, IA 52242, USA.
Mark S BlumbergDepartment of Psychological and Brain Sciences, University of Iowa, 340 Iowa Avenue, Iowa City, IA 52242, USA; Iowa Neuroscience Institute, University of Iowa, Iowa City, IA 52242, USA. Electronic address: mark-blumberg@uiowa.edu.
University of Iowa · US

Funding

University of Iowa Hawkeye Intellectual and Developmental Disabilities Research Center (Hawk-IDDRC)P50HD103556 · NICHD · UNIVERSITY OF IOWA · PI EDWIN TED G. ABEL, Lane Strathearn · 2021 to 2026
$8.5M
State-dependent sensory processing across early developmentR37HD081168 · NICHD · UNIVERSITY OF IOWA · PI BLUMBERG, MARK SAMUEL · 2014 to 2023
$5.1M
Cortical activity and phasic REM sleep in human newbornsR21HD095153 · NICHD · UNIVERSITY OF IOWA · PI BLUMBERG, MARK SAMUEL · 2018 to 2019
$385k
NICHD NIH HHS P50 HD103556NICHD NIH HHS R21 HD095153NICHD NIH HHS R37 HD081168
6 · The paper itself

Abstract

In humans and other mammals, the stillness of sleep is punctuated by bursts of rapid eye movements (REMs) and myoclonic twitches of the limbs.

Indexed as

MovementSleepSleep, Slow-WaveElectroencephalographyFeedback, SensoryHumansInfantSleep, REMcerebral palsycortexdevelopmentmyoclonic twitchingneural plasticitynon-REM sleeprapid eye movementsREM sleepsensorimotorsleep spindles

Identifiers

PMID34139191
PMCPMC8355086
OpenAlexW3168032414

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.