Evidence map›Paper›PMID 34139189›Full record

ArticleThe Annals of thoracic surgery2022

Outcomes of Extracorporeal Membrane Oxygenation in Patients With Severe Acute Respiratory Distress Syndrome Caused by COVID-19 Versus Influenza.

Emily Shih, John J Squiers, J Michael DiMaio, Timothy George, Jasjit Banwait, Kara Monday, Britton Blough, Dan Meyer, Gary S Schwartz

Abstract read
In one paragraph

Article in The Annals of thoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  10. Blood Product Utilization in Patients With COVID-19 on ECMO.The Journal of surgical research · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emily ShihDepartment of Surgery, Baylor University Medical Center, Dallas, Texas. Electronic address: emily.shih@bswhealth.org.
John J SquiersDepartment of Surgery, Baylor University Medical Center, Dallas, Texas; Department of Cardiothoracic Surgery, Baylor Scott and White The Heart Hospital, Plano, Texas.
J Michael DiMaioDepartment of Cardiothoracic Surgery, Baylor Scott and White The Heart Hospital, Plano, Texas.
Timothy GeorgeDepartment of Cardiothoracic Surgery, Baylor Scott and White The Heart Hospital, Plano, Texas.
Jasjit BanwaitBaylor Scott and White Research Institute, Dallas, Texas.
Kara MondayDepartment of Surgery, Baylor University Medical Center, Dallas, Texas.
Britton BloughDepartment of Surgery, Baylor University Medical Center, Dallas, Texas.
Dan MeyerDepartment of Cardiothoracic Surgery, Baylor University Medical Center, Dallas, Texas.
Gary S SchwartzDepartment of Cardiothoracic Surgery, Baylor University Medical Center, Dallas, Texas.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtracorporeal membrane oxygenation (ECMO) can be effective for refractory acute respiratory distress syndrome (ARDS) in patients with influenza, but its utility in patients with coronavirus disease 2019 (COVID-19) is uncertain. We compared outcomes of patients with refractory ARDS from COVID-19 and influenza placed on ECMO.

methodsWe conducted a retrospective analysis of 120 patients with refractory ARDS due to COVID-19 or influenza placed on ECMO at 2 referral centers from January 2013 to October 2020. Patient characteristics and clinical outcomes were compared. The primary endpoint was survival to discharge.

resultsBaseline characteristics and comorbidities were similar. During the study period, 53 patients with COVID-19 and 67 patients with influenza were supported. Venovenous ECMO was the predominant initial cannulation strategy in both groups (COVID 92.5% vs influenza 95.5%; P = .5). Survival to hospital discharge was 62.3% (33 of 53 patients) in the COVID-19 group and 64.2% (43 of 67 patients) in the influenza group (P = .8). In patients successfully decannulated, median length of time on ECMO was longer in COVID-19 patients (14 [interquartile range (IQR), 9-30] days vs influenza 10.5 [IQR, 6.8-14.3] days; P = .004). Among patients discharged alive, COVID-19 patients had longer overall length of stay (COVID-19 37 [IQR, 27-62] days vs influenza 13.5 [IQR, 9.3-24] days; P = .007).

conclusionsIn patients with refractory ARDS from COVID-19 or influenza placed on ECMO, there was no significant difference in survival to hospital discharge. In patients surviving to decannulation, the duration of ECMO support and total length of stay were longer in COVID-19 patients.

Indexed as

COVID-19Extracorporeal Membrane OxygenationInfluenza, HumanRespiratory Distress SyndromeHumansRetrospective StudiesSARS-CoV-2

Identifiers

PMID34139189
PMCPMC8204847

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.