ReviewCell systems2021
IonoBiology: The functional dynamics of the intracellular metallome, with lessons from bacteria.
Review in Cell systems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Metallomic Analysis of Vitreous Humor of the Human Eye-A Post-Mortem Multielemental Study.International journal of molecular sciences · 2026Article
- Various Ways to Be Negative: Biophysical Characterization of Polyanionic Biomolecules.The journal of physical chemistry. B · 2026Article
- Integrating hematological profile and biomarker analysis for metals and metalloids ecotoxicological assessment on Wallago catfish and Indian carp health in Head Siphon, Mailsi, Pakistan.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Crystal Structure and Functional Characterization of YjgK From Salmonella Typhimurium.Proteins · 2025Article
- Bioelectronic Delivery of Potassium Ions Controls Membrane Voltage and Growth Dynamics in Bacteria Biofilms.Biomedical materials & devices (New York, N.Y.) · 2025Article
- A novel cathelicidin TS-CATH derived fromComputational and structural biotechnology journal · 2024Article
- Characterization of two bacterial tyrosinases from the halophilic bacterium Hahella sp. CCB MM4 relevant for phenolic compounds oxidation in wetlands.FEBS open bio · 2024Article
- Nanovibrational Stimulation ofACS nano · 2024Article
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- Article
- Ion Signaling in Cell Motility and Development inBiomolecules · 2024Review
- Coinfecting phages impede each other's entry into the cell.Current biology : CB · 2024Article
- Determination of cinnamaldehyde, thymol and eugenol in essential oils by LC-MS/MS and antibacterial activity of them against bacteria.Scientific reports · 2024Article
- Intermittent proton bursts of single lactic acid bacteria.Chemical science · 2024Article
- Global control of cellular physiology by biomolecular condensates through modulation of electrochemical equilibria.bioRxiv : the preprint server for biology · 2023Article
- Cell-autonomous diversification in bacteria arises from calcium dynamics self-organizing at a critical point.Science advances · 2023Article
- Modeling control and transduction of electrochemical gradients in acid-stressed bacteria.iScience · 2023Article
- Membrane Targeted Azobenzene Drives Optical Modulation of Bacterial Membrane Potential.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Localized electrical stimulation triggers cell-type-specific proliferation in biofilms.Cell systems · 2022Article
- Measurement of the low-frequency charge noise of bacteria.Physical review. E · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Metal ions are essential for life and represent the second most abundant constituent (after water) of any living cell. While the biological importance of inorganic ions has been appreciated for over a century, we are far from a comprehensive understanding of the functional roles that ions play in cells and organisms. In particular, recent advances are challenging the traditional view that cells maintain constant levels of ion concentrations (ion homeostasis). In fact, the ionic composition (metallome) of cells appears to be purposefully dynamic. The scientific journey that started over 60 years ago with the seminal work by Hodgkin and Huxley on action potentials in neurons is far from reaching its end. New evidence is uncovering how changes in ionic composition regulate unexpected cellular functions and physiology, especially in bacteria, thereby hinting at the evolutionary origins of the dynamic metallome. It is an exciting time for this field of biology, which we discuss and refer to here as IonoBiology.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.