SynthesisPloS one2021
The effectiveness of peer-support for people living with HIV: A systematic review and meta-analysis.
Synthesis in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06716450 (A Study to Evaluate the Accuracy, Usability and Readability of the Multiplo® TP/HIV Antibody Self-Test Performed by Observed Intended Users in Canada and the Impact of Peer-led HIV and Syphilis Care Among People Experiencing Homelessness in Toronto), which is not on this map. Cited by 97 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Study to Evaluate the Accuracy, Usability and Readability of the Multiplo® TP/HIV Antibody Self-Test Performed by Observed Intended Users in Canada and the Impact of Peer-led HIV and Syphilis Care Among People Experiencing Homelessness in Toronto
Who cites it
97 citing papers in PubMed, 7 syntheses or guidelines pooled it, 148 citations in OpenAlex.
- Implementation components and delivery structures of adolescent peer navigation as a workforce model: a scoping review.BMC global and public health · 2026Pooled it
- People Living with HIV Experiences from Peer Support: A Meta-Synthesis.International journal of community based nursing and midwifery · 2026Pooled it
- Better Together?: A Systematic Review of the Effectiveness of HIV Prevention Interventions that Build or Strengthen Social Ties.AIDS and behavior · 2025Pooled it
- Psychoeducational interventions for people living with chronic communicable disease: a systematic review.BMJ open · 2024Pooled it
- Reasons for disengagement from antiretroviral care in the era of "Treat All" in low- or middle-income countries: a systematic review.Journal of the International AIDS Society · 2024Pooled it
- Towards evidence-based and inclusive models of peer support for long covid: A hermeneutic systematic review.Social science & medicine (1982) · 2023Pooled it
- Psychological and Social Impact of HIV on Women Living with HIV and Their Families in Low- and Middle-Income Asian Countries: A Systematic Search and Critical Review.International journal of environmental research and public health · 2022Pooled it
- Feasibility and Acceptability of Barbershop-Based HIV Prevention Among Heterosexual Men in Kalangala Islands, Uganda: Protocol for a Cluster Randomized Trial (HPTN 111).JMIR research protocols · 2026Trial
- Trial
- Community Connectedness and Its Association with Stigma and Viral Suppression Among MSM with HIV: Findings from HPTN 078.AIDS and behavior · 2026Article
- Digitally Adapting LGBTQ-Affirmative Cognitive Behavioral Therapy for Chinese Men Who Have Sex With Men Living With HIV: User-Centered Design Approach.Journal of medical Internet research · 2026Article
- Health factors, stigma, and psychosocial resources associated with self-rated health: a cross-sectional analysis of the People Living with HIV Stigma Index 2.0 in Bolivia.Lancet regional health. Americas · 2026Article
- Perspectives on peer recovery support for people experiencing homelessness: A qualitative study of key informants from national health care for the homeless programs.Journal of substance use and addiction treatment · 2026Article
- Do people with HIV really have the choice between oral and injectable ART? Evidence from a multicentric survey in the Swiss HIV cohort study.HIV medicine · 2026Article
- Social Support Across the Cancer Care Continuum in Malawi: Narratives from Cancer Survivors.SSM. Qualitative research in health · 2026Article
- Experiences and Outcomes of Peer Navigation and Support Interventions for Adolescents on HIV Treatment in Sub-Saharan Africa: A Qualitative Evidence Synthesis.International journal of environmental research and public health · 2026Review
- Enhancing care in alcohol-associated liver disease through peer support for alcohol use disorder.Hepatology communications · 2026Review
- Optimizing the patient journey: Insights from early implementation of long-acting cabotegravir and rilpivirine in four urban Ryan White-funded clinics in the United States.Journal of the International AIDS Society · 2026Article
- Peer Interventions for Hepatitis C Testing and Treatment in OECD Countries: A Systematic Scoping Review.Journal of viral hepatitis · 2026Article
- Moving from In-Person to Digital Delivery Models of HIV Peer Support Services in Response to COVID-19: A Qualitative Study.AIDS and behavior · 2026Article
37 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe practice of involving people living with HIV in the development and provision of healthcare has gained increasing traction. Peer-support for people living with HIV is assistance and encouragement by an individual considered equal, in taking an active role in self-management of their chronic health condition. The objective of this systematic review was to assess the effects of peer-support for people living with HIV.
methodsWe conducted a systematic review in accordance with international guidelines. Following systematic searches of eight databases until May 2020, two reviewers performed independent screening of studies according to preset inclusion criteria. We conducted risk of bias assessments and meta-analyses of the available evidence in randomised controlled trials (RCTs). The certainty of the evidence for each primary outcome was evaluated with the Grading of Recommendations Assessment, Development, and Evaluation system.
resultsAfter screening 219 full texts we included 20 RCTs comprising 7605 participants at baseline from nine different countries. The studies generally had low risk of bias. Main outcomes with high certainty of evidence showed modest, but superior retention in care (Risk Ratio [RR] 1.07; Confidence Interval [CI] 95% 1.02-1.12 at 12 months follow-up), antiretroviral therapy (ART) adherence (RR 1.06; CI 95% 1.01-1.10 at 3 months follow-up), and viral suppression (Odds Ratio up to 6.24; CI 95% 1.28-30.5 at 6 months follow-up) for peer-support participants. The results showed that the current state of evidence for most other main outcomes (ART initiation, CD4 cell count, quality of life, mental health) was promising, but too uncertain for firm conclusions.
conclusionsOverall, peer-support with routine medical care is superior to routine clinic follow-up in improving outcomes for people living with HIV. It is a feasible and effective approach for linking and retaining people living with HIV to HIV care, which can help shoulder existing services.
trial registrationCRD42020173433.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.