Evidence map›Paper›PMID 34137936›Full record

GuidelinePediatric radiology2021

European guideline for imaging in paediatric and adolescent rhabdomyosarcoma - joint statement by the European Paediatric Soft Tissue Sarcoma Study Group, the Cooperative Weichteilsarkom Studiengruppe and the Oncology Task Force of the European Society of Paediatric Radiology.

Roelof van Ewijk, Reineke A Schoot, Monika Sparber-Sauer, Simone A J Ter Horst, Nina Jehanno, Lise Borgwardt, Bart de Keizer, Johannes H M Merks, Alberto de Luca, Kieran McHugh and 4 more

Open access · hybridAbstract readPractice Guideline
In one paragraph

Guideline in Pediatric radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Whole-Body MRI VersusCancers · 2026
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  5. Utilizing [Cancers · 2026
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  9. Texture analysis and metabolic parameters ofEuropean journal of nuclear medicine and molecular imaging · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 5 countries.

Roelof van EwijkPrincess Máxima Centre for Paediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands. r.vanewijk-2@prinsesmaximacentrum.nl.ORCID 0000-0003-0339-6031
Reineke A SchootPrincess Máxima Centre for Paediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands.
Monika Sparber-SauerPaediatric Oncology, Olgahospital, Zentrum für Kinder-, Jugend- und Frauenmedizin, Klinikum Stuttgart, Stuttgart, Germany.
Simone A J Ter HorstPrincess Máxima Centre for Paediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands.
Nina JehannoDepartment of Nuclear Medicine, Institut Curie, Paris, France.
Lise BorgwardtDepartment of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen, Denmark.
Bart de KeizerPrincess Máxima Centre for Paediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands.
Johannes H M MerksPrincess Máxima Centre for Paediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands.
Alberto de LucaDepartment of Neurology, Brain Centre Rudolf Magnus, UMC Utrecht, Utrecht, the Netherlands.
Kieran McHughDepartment of Radiology, Great Ormond Street Hospital for Children, London, UK.
Thekla von KalleInstitute of Radiology Olgahospital, Zentrum für Kinder-, Jugend- und Frauenmedizin, Klinikum Stuttgart, Stuttgart, Germany.
Jürgen F SchäferDivision of Paediatric Radiology, Department of Radiology, University Hospital of Tübingen, Tübingen, Germany.
Rick R van RijnDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Cooperative Weichteilsarkom Studiengruppe Imaging Group, the European Society of Paediatric Radiology Oncology Task Force and the European Paediatric Soft Tissue Sarcoma Study Group Imaging Committee
Princess Máxima Center · NLOlgahospital · DEAmsterdam University Medical Centers · NLGreat Ormond Street Hospital · GBInstitut Curie · FRRigshospitalet · DKUniversity Children's Hospital Tübingen · DEUniversity Medical Center Utrecht · NL

Funding

Stichting Kinderen Kankervrij 357
6 · The paper itself

Abstract

Appropriate imaging is essential in the treatment of children and adolescents with rhabdomyosarcoma. For adequate stratification and optimal individualised local treatment utilising surgery and radiotherapy, high-quality imaging is crucial. The paediatric radiologist, therefore, is an essential member of the multi-disciplinary team providing clinical care and research. This manuscript presents the European rhabdomyosarcoma imaging guideline, based on the recently developed guideline of the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG) Imaging Committee. This guideline was developed in collaboration between the EpSSG Imaging Committee, the Cooperative Weichteilsarkom Studiengruppe (CWS) Imaging Group, and the Oncology Task Force of the European Society of Paediatric Radiology (ESPR). MRI is recommended, at diagnosis and follow-up, for the evaluation of the primary tumour and its relationship to surrounding tissues, including assessment of neurovascular structures and loco-regional lymphadenopathy. Chest CT along with [F-18]2-fluoro-2-deoxyglucose (FDG) positron emission tomography (PET)/CT or PET/MRI are recommended for the detection and evaluation of loco-regional and distant metastatic disease. Guidance on the estimation of treatment response, optimal long-term follow-up, technical imaging settings and standardised reporting are described. This European imaging guideline outlines the recommendations for imaging in children and adolescents with rhabdomyosarcoma, with the aim to harmonise imaging and to advance patient care.

Indexed as

RadiologyRhabdomyosarcomaSarcomaAdolescentChildHumansNeoplasm StagingPositron-Emission TomographyAdolescentChildConsensusDiagnosisMagnetic resonance imagingPositron emission tomography/computed tomographyRhabdomyosarcomaSarcomaStaging

Identifiers

PMID34137936
PMCPMC8426307
OpenAlexW3166591938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.