ArticleEuropean radiology2022
Volumetric ADC histogram analysis for preoperative evaluation of LVSI status in stage I endometrioid adenocarcinoma.
Article in European radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 25 citations in OpenAlex.
- Preoperative prediction of KRAS mutation in rectal cancer using a combined T2-weighted imaging radiomics and volumetric apparent diffusion coefficient histogram model.Abdominal radiology (New York) · 2026Article
- A multiparameter diagnostic model based on MRI volumetric ADC histogram and clinical variables accurately differentiates thymic epithelial tumors from mediastinal lymphomas.BMC medical imaging · 2026Article
- Association between histogram parameters of T2 weighted MRI data, WHO grade, tumor proliferation index and selected molecular markers in low-grade glioma.Frontiers in radiology · 2026Article
- Preoperative prediction of brain invasion in meningiomas: a comparison of diffusion kurtosis imaging and diffusion tensor imaging.BMC neurology · 2025Article
- Feasibility of ADC histogram analysis for predicting of postoperative recurrence in aggressive spinal tumors.Journal of bone oncology · 2025Article
- Application of a combined clinical prediction model based on enhanced T1-weighted image(T1WI) full volume histogram in peripheral nerve invasion (PNI) and lymphatic vessel invasion (LVI) in rectal cancer.Abdominal radiology (New York) · 2025Article
- Correlation Analysis of Apparent Diffusion Coefficient Histogram Parameters and Clinicopathologic Features for Prognosis Prediction in Uveal Melanoma.Investigative ophthalmology & visual science · 2024Article
- Histogram analysis of multiple diffusion models for predicting advanced non-small cell lung cancer response to chemoimmunotherapy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- Whole-tumor histogram analysis of postcontrast T1-weighted and apparent diffusion coefficient in predicting the grade and proliferative activity of adult intracranial ependymomas.Neuroradiology · 2024Article
- Development and external validation of a clinical-radiomics nomogram for preoperative prediction of LVSI status in patients with endometrial carcinoma.Journal of cancer research and clinical oncology · 2023Article
- Adenocarcinoma - success so far and the way ahead.EXCLI journal · 2023Article
- Evaluation of Amide Proton Transfer-Weighted Imaging for Risk Factors in Stage I Endometrial Cancer: A Comparison With Diffusion-Weighted Imaging and Diffusion Kurtosis Imaging.Frontiers in oncology · 2022Article
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7 authors at 2 institutions in 1 country.
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Abstract
objectivesTo investigate the value of volumetric ADC histogram metrics for evaluating lymphovascular space invasion (LVSI) status in stage I endometrioid adenocarcinoma (EAC).
methodsPreoperative MRI of 227 patients with stage I EAC were retrospectively analyzed. ADC histogram data were derived from the whole tumor with ROIs drawn on all slices of DWI scans (b = 0, 1000 s/mm
resultsThe minADC and meanADC and 10th, 25th, 50th, 75th, and 90th percentiles of ADC were significantly lower in LVSI-positive EACs compared with those in the LVSI-negative groups for stage I, Ia, and Ib EACs (all p < 0.05). MeanADC ≤ 0.857 × 10
conclusionVolumetric ADC histogram metrics might be helpful for the preoperative evaluation of LVSI status and personalized clinical management in patients with stage I EAC. KEY POINTS: • Volumetric ADC histogram analysis helps evaluate LVSI status preoperatively. • LVSI-positive EAC is associated with a reduction in multiple volumetric ADC histogram metrics. • MeanADC and the 90th percentile of ADC were shown to be best in evaluating LVSI- positivity in stage Ia and Ib EACs, respectively.
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