Evidence map›Paper›PMID 34137842›Full record

ArticleBioscience reports2021

Monocyte-to-albumin ratio as a novel predictor of long-term adverse outcomes in patients after percutaneous coronary intervention.

Zeng-Lei Zhang, Qian-Qian Guo, Jun-Nan Tang, Jian-Chao Zhang, Meng-Die Cheng, Feng-Hua Song, Zhi-Yu Liu, Kai Wang, Li-Zhu Jiang, Lei Fan and 6 more

Abstract read
In one paragraph

Article in Bioscience reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  15. The age, NT-proBNP, and Ejection Fraction Score as a Novel Predictor of Clinical Outcomes in CAD Patients After PCI.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Zeng-Lei Zhang *Department of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Qian-Qian Guo *Department of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Jun-Nan TangDepartment of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Jian-Chao ZhangDepartment of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Meng-Die ChengDepartment of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Feng-Hua SongDepartment of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Zhi-Yu LiuDepartment of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Kai WangDepartment of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Li-Zhu JiangDepartment of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Lei FanDepartment of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Xiao-Ting YueDepartment of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Yan BaiDepartment of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Xin-Ya DaiDepartment of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Ru-Jie ZhengDepartment of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Ying-Ying ZhengDepartment of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.ORCID 0000-0003-0003-4270
Jin-Ying ZhangDepartment of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMonocyte count and serum albumin (Alb) have been proven to be involved in the process of systemic inflammation. Therefore, we investigated the prognostic value of monocyte-to-albumin ratio (MAR) in patients who underwent percutaneous coronary intervention (PCI).

methodsWe enrolled a total of 3561 patients in the present study from January 2013 to December 2017. They were divided into two groups according to MAR cut-off value (MAR < 0.014, n=2220; MAR ≥ 0.014, n=1119) as evaluated by receiver operating characteristic (ROC) curve. The average follow-up time was 37.59 ± 22.24 months.

resultsThe two groups differed significantly in the incidences of all-cause mortality (ACM; P<0.001), cardiac mortality (CM; P<0.001), major adverse cardiovascular events (MACEs; P=0.038), and major adverse cardiovascular and cerebrovascular events (MACCEs; P=0.037). Multivariate Cox regression analyses revealed MAR as an independent prognostic factor for ACM and CM. The incidence of ACM increased by 56.5% (hazard ratio [HR] = 1.565; 95% confidence interval [CI], 1.086-2.256; P=0.016) and that of CM increased by 76.3% (HR = 1.763; 95% CI, 1.106-2.810; P=0.017) in patients in the higher-MAR group. Kaplan-Meier survival analysis suggested that patients with higher MAR tended to have an increased accumulated risk of ACM (Log-rank P<0.001) and CM (Log-rank P<0.001).

conclusionThe findings of the present study suggested that MAR was a novel independent predictor of long-term mortality in patients who underwent PCI.

Indexed as

MonocytesAgedBiomarkersCoronary Artery DiseaseFemaleHumansMaleMiddle AgedPercutaneous Coronary InterventionPredictive Value of TestsRetrospective StudiesRisk AssessmentRisk FactorsSerum Albumin, HumanTime FactorsTreatment OutcomeALB protein, humanBiomarkersSerum Albumin, Humancoronary artery diseasemonocyte-to-albumin ratiomortalitypercutaneous coronary interventionprognosis

Identifiers

PMID34137842
PMCPMC8243340

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.