Evidence map›Paper›PMID 34137758›Full record

ArticleSoft matter2021

Transient mechanical interactions between cells and viscoelastic extracellular matrix.

Brandon Slater, Jing Li, Dhiraj Indana, Yihao Xie, Ovijit Chaudhuri, Taeyoon Kim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Soft matter, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Mechanobiological Dynamics-Inspired Mechanomodulatory Biomaterials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Inflammatory Microenvironment of Skin Wounds.Frontiers in immunology · 2022
    Review
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Brandon SlaterWeldon School of Biomedical Engineering, Purdue University, 206 S Martin Jischke Dr, West Lafayette, IN 47907, USA. kimty@purdue.edu.
Jing LiWeldon School of Biomedical Engineering, Purdue University, 206 S Martin Jischke Dr, West Lafayette, IN 47907, USA. kimty@purdue.edu.
Dhiraj IndanaDepartment of Mechanical Engineering, Stanford University, 440 Escondido Mall, Stanford, CA, 94305, USA.ORCID http://orcid.org/0000-0002-8644-5048
Yihao XieSchool of Mechanical Engineering, Purdue University, 585 Purdue Mall, West Lafayette, IN 47907, USA.
Ovijit ChaudhuriDepartment of Mechanical Engineering, Stanford University, 452 Escondido Mall, Stanford, CA, 94305, USA.ORCID http://orcid.org/0000-0002-9287-3401
Taeyoon KimWeldon School of Biomedical Engineering, Purdue University, 206 S Martin Jischke Dr, West Lafayette, IN 47907, USA. kimty@purdue.edu.ORCID http://orcid.org/0000-0002-5588-8532

Funding

Universal Roles of Force Generation and Transmission in Biological SystemsR01GM126256 · NIGMS · PURDUE UNIVERSITY · PI KIM, TAEYOON · 2017 to 2021
$2.3M
NIGMS NIH HHS R01 GM126256
6 · The paper itself

Abstract

During various physiological processes, such as wound healing and cell migration, cells continuously interact mechanically with a surrounding extracellular matrix (ECM). Contractile forces generated by the actin cytoskeleton are transmitted to a surrounding ECM, resulting in structural remodeling of the ECM. To better understand how matrix remodeling takes place, a myriad of

Indexed as

CollagenExtracellular MatrixCell MovementFibroblastsStress, MechanicalViscosityCollagen

Identifiers

PMID34137758
PMCPMC8695121

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.