Evidence map›Paper›PMID 34137665›Full record

ReviewPharmacogenomics2021

Pharmacogenomics education, research and clinical implementation in the state of Minnesota.

Jeffrey R Bishop, R Stephanie Huang, Jacob T Brown, Pawel Mroz, Steven G Johnson, Josiah D Allen, Suzette J Bielinski, Julie England, Joel F Farley, David Gregornik and 26 more

Abstract readReview
In one paragraph

Review in Pharmacogenomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  10. Article
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors.

Jeffrey R BishopDepartment of Experimental & Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA.ORCID 0000-0001-7653-8980
R Stephanie HuangDepartment of Experimental & Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA.
Jacob T BrownDepartment of Pharmacy Practice & Pharmaceutical Sciences, University of Minnesota College of Pharmacy, Duluth, MN 55812, USA.
Pawel MrozDepartment of Laboratory Medicine & Pathology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Steven G JohnsonInstitute for Health Informatics, University of Minnesota, Minneapolis, MN 55455, USA.
Josiah D AllenUniversity of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA.
Suzette J BielinskiDepartment of Quantitative Health Sciences, Division of Epidemiology, Mayo Clinic, Rochester, MN 55905, USA.
Julie EnglandOneOme, LLC, Minneapolis, MN 55413, USA.
Joel F FarleyDepartment of Pharmaceutical Care & Health Systems, University of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA.
David GregornikPharmacogenomics Program, Children's Minnesota, Minneapolis, MN 55407, USA.ORCID 0000-0001-9856-7205
Jyothsna GiriMayo Clinic Center for Individualized Medicine, Mayo Clinic College of Medicine & Science, Mayo Clinic, Rochester, MN 55905, USA.
Christine KrogerAllina Health, Minneapolis, MN 55407, USA.
Susie E LongMHealth Fairview. Acute Care Pharmacy Services, Minneapolis, MN 55455, USA.
Tiana LuczakDepartment of Pharmacy Practice & Pharmaceutical Sciences, University of Minnesota College of Pharmacy, Duluth, MN 55812, USA.ORCID 0000-0001-9398-7155
Erin J McGonagleDepartment of Experimental & Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA.
Sisi MaInstitute for Health Informatics, University of Minnesota, Minneapolis, MN 55455, USA.
Eric T MateyDepartment of Pharmacy, Mayo Clinic College of Medicine & Science, Mayo Clinic, Rochester, MN 55905, USA.
Pinar K MandicDepartment of Finance, University of Minnesota Carlson School of Management, Minneapolis, MN 55455, USA.
Ann M MoyerDepartment of Laboratory Medicine & Pathology, Mayo Clinic College of Medicine & Science, Mayo Clinic, Rochester, MN 55905, USA.
Wayne T NicholsonDepartment of Anesthesiology & Perioperative Medicine, Mayo Clinic College of Medicine & Science, Mayo Clinic, Rochester, MN 55905, USA.
Natasha PetrySanford Health Imagenetics, Sioux Falls, SD 57105, USA.ORCID 0000-0001-5089-9286
Pamala A PawloskiHealthPartners Institute, Minneapolis, MN 55440, USA.
Allyson SchlichteFairview Pharmacy Services, LLC, Minneapolis, MN 55414, USA.
Stephen W SchondelmeyerDepartment of Pharmaceutical Care & Health Systems, University of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA.
Randall D SeifertDepartment of Pharmacy Practice & Pharmaceutical Sciences, University of Minnesota College of Pharmacy, Duluth, MN 55812, USA.
Marilyn K SpeedieDepartment of Medicinal Chemistry, University of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA.
David StenehjemDepartment of Pharmacy Practice & Pharmaceutical Sciences, University of Minnesota College of Pharmacy, Duluth, MN 55812, USA.ORCID 0000-0002-1831-285X
Robert J StrakaDepartment of Experimental & Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA.
Jason WachtlGeritom Medical, Inc, Bloomington, MN 55438, USA.
Stephen C WaringEssentia Institute of Rural Health, Duluth, MN 55805, USA.
Brian Van NessDepartment of Genetics, Cell Biology & Development, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Heather A ZierhutDepartment of Genetics, Cell Biology & Development, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Constantin AliferisInstitute for Health Informatics, University of Minnesota, Minneapolis, MN 55455, USA.
Susan M WolfLaw School, Medical School, Consortium on Law & Values in Health, Environment & the Life Sciences, University of Minnesota, Minneapolis, MN 55455, USA.
Catherine A McCartyDepartment of Family Medicine & Biobehavioral Health, University of Minnesota Medical School, Duluth, MN 55812, USA.
Pamala A JacobsonDepartment of Experimental & Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, MN 55455, USA.

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
Institutional Career Development CoreKL2TR002492 · NCATS · UNIVERSITY OF MINNESOTA · PI INGBAR, DAVID H · 2018 to 2022
$6.3M
Minnesota Learning Health System Mentored Career Development Program (MN-LHS)K12HS026379 · AHRQ · UNIVERSITY OF MINNESOTA · PI BEEBE, TIMOTHY, LINZER, MARK · 2018 to 2022
$2.9M
AHRQ HHS K12 HS026379NCATS NIH HHS KL2 TR002492NCATS NIH HHS UL1 TR002494
6 · The paper itself

Abstract

Several healthcare organizations across Minnesota have developed formal pharmacogenomic (PGx) clinical programs to increase drug safety and effectiveness. Healthcare professional and student education is strong and there are multiple opportunities in the state for learners to gain workforce skills and develop advanced competency in PGx. Implementation planning is occurring at several organizations and others have incorporated structured utilization of PGx into routine workflows. Laboratory-based and translational PGx research in Minnesota has driven important discoveries in several therapeutic areas. This article reviews the state of PGx activities in Minnesota including educational programs, research, national consortia involvement, technology, clinical implementation and utilization and reimbursement, and outlines the challenges and opportunities in equitable implementation of these advances.

Indexed as

Education, Pharmacy, GraduatePharmacogenomic TestingBiomedical ResearchHealth PersonnelHumansMinnesotaPharmacogeneticsimplementationMinnesotapharmacogenomics

Identifiers

PMID34137665
PMCPMC8265281

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.