Evidence map›Paper›PMID 34137407›Full record

ReviewLab on a chip2021

Recent advances in integrated solid-state nanopore sensors.

Mahmudur Rahman, Mohammad Julker Neyen Sampad, Aaron Hawkins, Holger Schmidt

Abstract readReview
In one paragraph

Review in Lab on a chip, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Threading of Single Protein Molecules Through a Solid-State Nanopore.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Solid-State Nanopores for Biomolecular Analysis and Detection.Advances in biochemical engineering/biotechnology · 2024
    Review
  17. Article
  18. Article
  19. Localized Nanopore Fabrication via Controlled Breakdown.Nanomaterials (Basel, Switzerland) · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mahmudur RahmanSchool of Engineering, University of California Santa Cruz, 1156 High Street, Santa Cruz, CA, 95064 USA. hschmidt@soe.ucsc.edu and Dhaka University of Engineering & Technology, Gazipur, Bangladesh.ORCID http://orcid.org/0000-0001-9175-0744
Mohammad Julker Neyen SampadSchool of Engineering, University of California Santa Cruz, 1156 High Street, Santa Cruz, CA, 95064 USA. hschmidt@soe.ucsc.edu.ORCID http://orcid.org/0000-0003-0725-9747
Aaron HawkinsECEn Department, Brigham Young University, 459 Clyde Building, Provo, UT, 84602 USA.
Holger SchmidtSchool of Engineering, University of California Santa Cruz, 1156 High Street, Santa Cruz, CA, 95064 USA. hschmidt@soe.ucsc.edu.ORCID http://orcid.org/0000-0003-2340-8108

Funding

Nanopore-based multi-target analysis of Zika virus infectionR01EB028608 · NIBIB · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI SCHMIDT, HOLGER · 2019 to 2022
$2.7M
NIBIB NIH HHS R01 EB028608
6 · The paper itself

Abstract

The advent of single-molecule probing techniques has revolutionized the biomedical and life science fields and has spurred the development of a new class of labs-on-chip based on powerful biosensors. Nanopores represent one of the most recent and most promising single molecule sensing paradigms that is seeing increased chip-scale integration for improved convenience and performance. Due to their physical structure, nanopores are highly sensitive, require low sample volume, and offer label-free, amplification-free, high-throughput real-time detection and identification of biomolecules. Over the last 25 years, nanopores have been extensively employed to detect a variety of biomolecules with a growing range of applicatons ranging from nucleic acid sequencing to ultrasensitive diagnostics to single-molecule biophysics. Nanopores, in particular those in solid-state membranes, also have the potential for integration with other technologies such as optics, plasmonics, microfluidics, and optofluidics to perform more complex tasks for an ever-expanding demand. A number of breakthrough results using integrated nanopore platforms have already been reported, and more can be expected as nanopores remain the focus of innovative research and are finding their way into commercial instruments. This review provides an overview of different aspects and challenges of nanopore technology with a focus on chip-scale integration of solid-state nanopores for biosensing and bioanalytical applications.

Indexed as

Biosensing TechniquesNanoporesBase SequenceNanotechnology

Identifiers

PMID34137407
PMCPMC8372664

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.