Evidence map›Paper›PMID 34137181›Full record

ArticleBasic & clinical pharmacology & toxicology2021

Causes of discrepancies between medications listed in the national electronic prescribing system and patients' actual use of medications.

Cille Bülow, Josefine D S V Noergaard, Kirstine Ullitz Faerch, Caroline Pontoppidan, Janne Unkerskov, Karl Sebastian Johansson, Jonatan Kornholt, Mikkel B Christensen

Abstract read
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In one paragraph

Article in Basic & clinical pharmacology & toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Accuracy of an electronic prescribing system for standard treatments.European journal of hospital pharmacy : science and practice · 2023
    Article
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cille BülowDepartment of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-6736-9601
Josefine D S V NoergaardThe Hospital Pharmacy, The Capital Region of Denmark, Bispebjerg and Hillerød Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-9179-3565
Kirstine Ullitz FaerchThe Hospital Pharmacy, The Capital Region of Denmark, Bispebjerg and Hillerød Hospital, University of Copenhagen, Copenhagen, Denmark.
Caroline PontoppidanThe Hospital Pharmacy, The Capital Region of Denmark, Bispebjerg and Hillerød Hospital, University of Copenhagen, Copenhagen, Denmark.
Janne UnkerskovQuality in General Practice in the Capital Region of Denmark (KAP-H), Hillerød, Denmark.
Karl Sebastian JohanssonDepartment of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-2125-4555
Jonatan KornholtDepartment of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-2662-4519
Mikkel B ChristensenDepartment of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-8774-1797

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Discrepancies between registered prescriptions and patients' actual use of medications are described as frequent and often resulting in adverse medication events. We aimed to assess the extent of and causes behind discrepancies between medications listed in the Danish national prescription system (Shared Medication Record) and patients' actual use of medications. We prospectively reconciled medication for 260 consecutively admitted polypharmacy patients (>50 years and ≥5 prescriptions) at two hospitals in the Capital Region of Denmark. The type of discrepancies were determined and the cause of the discrepancies were evaluated as primarily caused by (1) the patient (i.e., intentional or unintentional non-adherence) or (2) the health care system (i.e., lack of appropriate update of the SMR by physicians in primary or secondary care). There was a median of 12 [IQR 9-15] medications listed and 3 [IQR 1-5] medication discrepancies per patient (total n = 925). The majority (53%) of discrepancies were caused by the health care system, 32% were caused by the patients, of which 70% were intentional non-adherence, and 15% had an indeterminable cause. In conclusion, discrepancies between medications listed in the Shared Medication Record and actual use of medications were frequent and were most often caused by clinicians not updating the prescription information.

Indexed as

AgedAged, 80 and overDrug PrescriptionsElectronic PrescribingFemaleHumansMaleMedication ErrorsMedication ReconciliationMiddle AgedPolypharmacydrug informationprescription of drugsrational pharmacotherapy

Identifiers

PMID34137181

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.