Evidence map›Paper›PMID 34137079›Full record

ArticleJournal of cardiac surgery2021

Prioritizing heart transplantation during the COVID-19 pandemic.

Keki R Balsara, Zakiur Rahaman, Emily Sandhaus, Jordan Hoffman, Sandip Zalawadiya, William McMaster, Joann Lindenfeld, Mark Wigger, Tarek Absi, Douglas M Brinkley and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiac surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Keki R BalsaraDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0002-3502-5705
Zakiur RahamanDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Emily SandhausDivision of Cardiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Jordan HoffmanDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Sandip ZalawadiyaDivision of Cardiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
William McMasterDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Joann LindenfeldDivision of Cardiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Mark WiggerDivision of Cardiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Tarek AbsiDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Douglas M BrinkleyDivision of Cardiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Jonathan MenachemDivision of Cardiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Lynn PunnooseDivision of Cardiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Suzie SacksDivision of Cardiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Kelly SchlendorfDivision of Cardiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Ashish S ShahDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19) has significantly impacted the healthcare landscape in the United States in a variety of ways including a nation-wide reduction in operative volume. The impact of COVID-19 on the availability of donor organs and the impact on solid organ transplant remains unclear. We examine the impact of COVID-19 on a single, large-volume heart transplant program.

methodsA retrospective chart review was performed examining all adult heart transplants performed at a single institution between March 2020 and June 2020. This was compared to the same time frame in 2019. We examined incidence of primary graft dysfunction, continuous renal replacement therapy (CRRT) and 30-day survival.

resultsFrom March to June 2020, 43 orthotopic heart transplants were performed compared to 31 performed during 2019. Donor and recipient demographics demonstrated no differences. There was no difference in 30-day survival. There was a statistically significant difference in incidence of postoperative CRRT (9/31 vs. 3/43; p = .01). There was a statistically significant difference in race (23 W/8B/1AA vs. 30 W/13B; p = .029).

conclusionWe demonstrate that a single, large-volume transplant program was able to grow volume with little difference in donor variables and clinical outcomes following transplant. While multiple reasons are possible, most likely the reduction of volume at other programs allowed us to utilize organs to which we would not have previously had access. More significantly, our growth in volume was coupled with no instances of COVID-19 infection or transmission amongst patients or staff due to an aggressive testing and surveillance program.

Indexed as

COVID-19Heart TransplantationTissue and Organ ProcurementAdultHumansPandemicsRetrospective StudiesSARS-CoV-2Tissue DonorsUnited StatesCOVID-19heart transplantationresource allocation

Identifiers

PMID34137079
PMCPMC8447084

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.