Evidence map›Paper›PMID 34137002›Full record

ArticleMolecular imaging and biology2021

Selective Imaging of Lung Macrophages Using [

Delphine L Chen, Eugene Agapov, Kangyun Wu, Jacquelyn T Engle, Kiran Kumar Solingapuram Sai, Elizabeth Arentson, Katherine J Spayd, Kirby T Moreland, Kelsey Toth, Derek E Byers and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular imaging and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Total-Body Multiparametric PET Quantification ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  5. Article
  6. Review
  7. Non-invasive quantification of acute macrophagic lung inflammation with [European journal of nuclear medicine and molecular imaging · 2022
    Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Delphine L ChenDivision of Radiological Sciences and Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA. dlchen7@uw.edu.ORCID http://orcid.org/0000-0002-0150-5401
Eugene AgapovDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Kangyun WuDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Jacquelyn T EngleDivision of Radiological Sciences and Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Kiran Kumar Solingapuram SaiDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Elizabeth ArentsonDivision of Radiological Sciences and Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Katherine J SpaydDivision of Radiological Sciences and Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Kirby T MorelandDivision of Radiological Sciences and Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Kelsey TothDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Derek E ByersDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Richard A PierceDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Jeffrey J AtkinsonDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Richard LaforestDivision of Radiological Sciences and Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Andrew E GelmanDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Michael J HoltzmanDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Washington University in St. Louis · USMallinckrodt (United States) · USSeattle Cancer Care Alliance · USWake Forest University · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
Defining and Controlling Airway DiseaseR35HL145242 · NHLBI · WASHINGTON UNIVERSITY · PI HOLTZMAN, MICHAEL J · 2019 to 2025
$6.6M
POSITRON EMISSION TOMOGRAPHIC IMAGING OF LUNG TRANSPLANTR01HL121218 · NHLBI · WASHINGTON UNIVERSITY · PI CHEN, DELPHINE L, GELMAN, ANDREW ERIC · 2014 to 2017
$2.8M
IMAGING MACROPHAGE ACTIVATION IN CHRONIC OBSTRUCTIVE PULMONARY DISEASER01HL116389 · NHLBI · WASHINGTON UNIVERSITY · PI CHEN, DELPHINE L · 2012 to 2014
$1.1M
NCI NIH HHS P30 CA91842NHLBI NIH HHS R01 HL116389NHLBI NIH HHS R01 HL121218NHLBI NIH HHS R35 HL145242NIH HHS R01 HL116389NIH HHS R01 HL121218
6 · The paper itself

Abstract

purposeWe tested whether the translocator protein (TSPO)-targeted positron emission tomography (PET) tracer, N-acetyl-N-(2-[ PROCEDURES: MicroPET imaging quantified [

resultsIn Wt mice, [

conclusionsPET imaging with [

Indexed as

Fluorodeoxyglucose F18Positron-Emission TomographyAnimalsHumansLungMacrophagesMiceMice, Inbred C57BLReceptors, GABAFluorodeoxyglucose F18Receptors, GABATSPO protein, humanChronic obstructive pulmonary diseaseLung inflammationMacrophageMacrophage polarizationPositron emission tomographyTranslocator protein

Identifiers

PMID34137002
PMCPMC13286733
OpenAlexW3170385178

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.