Evidence map›Paper›PMID 34136817›Full record

ArticleRadiology. Artificial intelligence2021

Three-dimensional U-Net Convolutional Neural Network for Detection and Segmentation of Intracranial Metastases.

Jeffrey D Rudie, David A Weiss, John B Colby, Andreas M Rauschecker, Benjamin Laguna, Steve Braunstein, Leo P Sugrue, Christopher P Hess, Javier E Villanueva-Meyer

Open access · greenAbstract read
In one paragraph

Article in Radiology. Artificial intelligence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 57 citations in OpenAlex.

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  18. Computational Modeling and AI in Radiation Neuro-Oncology and Radiosurgery.Advances in experimental medicine and biology · 2024
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  19. Improved robustness for deep learning-based segmentation of multi-center myocardial perfusion cardiovascular MRI datasets using data-adaptive uncertainty-guided space-time analysis.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jeffrey D RudieDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143.ORCID https://orcid.org/0000-0001-8609-8421
David A WeissDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143.ORCID https://orcid.org/0000-0002-7494-2987
John B ColbyDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143.
Andreas M RauscheckerDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143.ORCID https://orcid.org/0000-0003-0633-9876
Benjamin LagunaDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143.ORCID https://orcid.org/0000-0001-6881-1078
Steve BraunsteinDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143.
Leo P SugrueDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143.ORCID https://orcid.org/0000-0001-7315-4519
Christopher P HessDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143.ORCID https://orcid.org/0000-0002-5132-5302
Javier E Villanueva-MeyerDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143.ORCID https://orcid.org/0000-0002-5910-0757
University of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo develop and validate a neural network for automated detection and segmentation of intracranial metastases on brain MRI studies obtained for stereotactic radiosurgery treatment planning. MATERIALS AND

methodsIn this retrospective study, 413 patients (average age, 61 years ± 12 [standard deviation]; 238 women) with a total of 5202 intracranial metastases (median volume, 0.05 cm

resultsThe median Dice score for segmenting enhancing metastases in the test set was 0.75 (interquartile range, 0.63-0.84). There were strong correlations between manually segmented and predicted metastasis volumes (

conclusionA 3D U-Net-based convolutional neural network was able to segment brain metastases with high accuracy and perform detection at the level of human interrater reliability for metastases larger than 6 mm.

Identifiers

PMID34136817
PMCPMC8204134
OpenAlexW3135293111

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.