ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2021
Hippocampal subfield volumes are associated with verbal memory after first-ever ischemic stroke.
Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Chronic Stroke Sensorimotor Impairment Is Related to Smaller Hippocampal Volumes: An ENIGMA Analysis.Journal of the American Heart Association · 2022Pooled it
- Longitudinal evaluation of hippocampal subfields volumes and episodic memory in breast cancer patients and healthy controls.Brain imaging and behavior · 2026Article
- Efficient multi-phenotype genome-wide analysis identifies genetic associations for unsupervised deep-learning-derived high-dimensional brain imaging phenotypes.medRxiv : the preprint server for health sciences · 2024Article
- Alterations of contralesional hippocampal subfield volumes and relations to cognitive functions in patients with unilateral stroke.Brain and behavior · 2024Article
- Cortical structural changes after subcortical stroke: Patterns and correlates.Human brain mapping · 2023Observational
- Sex Differences in the Long-Term Consequences of Stroke.Current topics in behavioral neurosciences · 2023Review
- Hippocampal subfield volumes in treatment resistant depression and serial ketamine treatment.Frontiers in psychiatry · 2023Article
- Neurodegeneration Over 3 Years Following Ischaemic Stroke: Findings From the Cognition and Neocortical Volume After Stroke Study.Frontiers in neurology · 2021Article
- Hippocampal subfield volumes are associated with verbal memory after first-ever ischemic stroke.Alzheimer's & dementia (Amsterdam, Netherlands) · 2021Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionHippocampal subfield volumes are more closely associated with cognitive impairment than whole hippocampal volume in many diseases. Both memory and whole hippocampal volume decline after stroke. Understanding the subfields' temporal evolution could reveal valuable information about post-stroke memory.
methodsWe sampled 120 participants (38 control, 82 stroke), with cognitive testing and 3T-MRI available at 3 months and 3 years, from the Cognition and Neocortical Volume after Stroke (CANVAS) study. Verbal memory was assessed using the Hopkins Verbal Learning Test-Revised. Subfields were delineated using FreeSurfer. We used partial Pearson's correlation to assess the associations between subfield volumes and verbal memory scores, adjusting for years of education, sex, and stroke side.
resultsThe left cornu ammonis areas 2/3 and hippocampal tail volumes were significantly associated with verbal memory 3-month post-stroke. At 3 years, the associations became stronger and involved more subfields. DISCUSSION: Hippocampal subfield volumes may be a useful biomarker for post-stroke cognitive impairment.
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Registered trials
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