Evidence map›Paper›PMID 34136580›Full record

Observational studyJournal of diabetes research2021

Association of Body Fat Percentage with Time in Range Generated by Continuous Glucose Monitoring during Continuous Subcutaneous Insulin Infusion Therapy in Type 2 Diabetes.

Yuting Ruan, Jiana Zhong, Rongping Chen, Zhen Zhang, Dixing Liu, Jia Sun, Hong Chen

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of diabetes research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yuting RuanDepartment of Endocrinology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 Guangdong, China.
Jiana ZhongDepartment of Endocrinology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 Guangdong, China.
Rongping ChenDepartment of Endocrinology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 Guangdong, China.
Zhen ZhangDepartment of Endocrinology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 Guangdong, China.
Dixing LiuDepartment of Endocrinology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 Guangdong, China.
Jia SunDepartment of Endocrinology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 Guangdong, China.ORCID https://orcid.org/0000-0001-9617-5865
Hong ChenDepartment of Endocrinology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 Guangdong, China.ORCID https://orcid.org/0000-0002-6317-9955
Zhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is a crucial risk factor associated with type 2 diabetes mellitus (T2DM). Excessive accumulation of body fat may affect the glycemia control in T2DM. This study investigated the relationship between body fat percentage and time in range (TIR) assessed by continuous glucose monitoring (CGM) during short-term continuous subcutaneous insulin infusion (CSII) therapy in T2DM patients.

methodA total of 85 T2DM patients were recruited in this cross-sectional study. All participants underwent 72 h CGM period during short-term CSII therapy. TIR was defined as the percentage of time spent within the target glucose range of 3.9-10.0 mmol/L. Body composition was measured using bioelectrical impedance analysis (BIA) and overfat was defined as an amount of body fat of at least 25% of total body mass for men or at least 30% for women. Multiple linear regression models were used to evaluate the independent association of body fat percentage with TIR after adjusting for confounding factors.

resultsCompared with normal fat T2DM patients, individual with a higher body fat percentage exhibited lower levels of TIR (

conclusionsBody fat percentage was significantly associated with TIR in T2DM during short-term CSII therapy. Reduction of body fat may be an important therapeutic target to improve glycemic control in high body fat T2DM patients, who may benefit less from intensive insulin treatment.

Indexed as

AdiposityBlood Glucose Self-MonitoringGlycemic ControlInsulin Infusion SystemsAgedBiomarkersBlood GlucoseClinical Decision-MakingCross-Sectional StudiesDiabetes Mellitus, Type 2Electric ImpedanceFemaleHumansHypoglycemic AgentsInfusions, SubcutaneousInsulinBiomarkersBlood GlucoseHypoglycemic AgentsInsulin

Identifiers

PMID34136580
PMCPMC8177984
OpenAlexW3169432464

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.