ArticleBioMed research international2021
Biofilm Formation by Pathogens Causing Ventilator-Associated Pneumonia at Intensive Care Units in a Tertiary Care Hospital: An Armor for Refuge.
Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 52 citations in OpenAlex.
- Protecting Newborns from Multidrug-Resistant Infections: The Emerging Role of Bacteriophages.Viruses · 2026Review
- Phytochemical profile, antioxidant, antimicrobial activity, antibiofilm, cytotoxicity, and HR-LCMS of Tribulus terrestris.Journal, genetic engineering & biotechnology · 2026Article
- Pathogen Characteristic of Biofilm-Related CAUTI in the Intensive Care Unit.International journal of microbiology · 2026Article
- Fungal biofilms in human health and disease.Nature reviews. Microbiology · 2025Review
- Article
- Assessment of bacterial positivity rate changes in anesthesia machine internal circuits within recovery rooms and associated risk factors.BMC anesthesiology · 2025Observational
- Construction and Validation of a Risk Prediction Model for Ventilator-Associated Pneumonia in Mechanically Ventilated Pediatric Patients.Journal of nursing management · 2025Article
- Biofilm Production in Intensive Care Units: Challenges and Implications.Pathogens (Basel, Switzerland) · 2024Review
- The role of human extracellular matrix proteins in defining Staphylococcus aureus biofilm infections.FEMS microbiology reviews · 2024Review
- Treatment and Management ofInfection and drug resistance · 2024Review
- Association of biofilm formation, antimicrobial resistance, clinical characteristics, and clinical outcomes among Acinetobacter baumannii isolates from patients with ventilator-associated pneumonia.The clinical respiratory journal · 2024Article
- Facile Modification of Medical-Grade Silicone for Antimicrobial Effectiveness and Biocompatibility: A Potential Therapeutic Strategy against Bacterial Biofilms.ACS applied materials & interfaces · 2023Article
- Microbial Biofilms: Applications, Clinical Consequences, and Alternative Therapies.Microorganisms · 2023Review
- Resistance patterns of bacterial pathogens causing lower respiratory tract infections: Aleppo-Syria.Annals of medicine and surgery (2012) · 2023Article
- Article
- In Vitro Assessment on Designing Novel Antibiofilms ofMolecules (Basel, Switzerland) · 2022Article
- Review
- Multi-drug resistant gram-negative bacterial pneumonia: etiology, risk factors, and drug resistance patterns.Pneumonia (Nathan Qld.) · 2022Review
- Molecular Mechanisms Mediating Ceftazidime/Avibactam Resistance Amongst Carbapenem-ResistantInfection and drug resistance · 2022Article
- Rapid detection ofFrontiers in cellular and infection microbiology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEmerging threat of drug resistance among pathogens causing ventilator-associated pneumonia (VAP) has resulted in higher hospital costs, longer hospital stays, and increased hospital mortality. Biofilms in the endotracheal tube of ventilated patients act as protective shield from host immunity. They induce chronic and recurrent infections that defy common antibiotics. This study intended to determine the biofilm produced by pathogens causing VAP and their relation with drug resistance.
methodsBronchoalveolar lavage and deep tracheal aspirates (
resultsSignificant microbial growth was seen in 78.6% of the total samples with 52.7% monomicrobial, 45.5% polymicrobial, and 1.8% fungal infection. Among the 71 isolates obtained, bulk was gram-negative (
conclusionGram-negative nonfermenter bacteria account for the bulk of nosocomial pneumonia. MDR, ESBL, and MBL production was preponderant among the biofilm producers. The rampant spread of drug resistance among biofilm producers is summoning novel interventions to combat multidrug resistance.
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