Evidence map›Paper›PMID 34136567›Full record

ArticleBioMed research international2021

Silencing Cardiac Troponin I-Interacting Kinase Reduces Lipopolysaccharide-Induced Sepsis-Induced Myocardial Dysfunction in Rat by Regulating Apoptosis-Related Proteins.

Dong Yang, Yanzhou Jiang, Haixia Qian, Xiaomin Liu, Liguo Mi

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Dong YangDepartment of Emergency (Xiangjiang Hospital), The Third Hospital of Hebei Medical University, Shijiazhuang 050051, China.ORCID https://orcid.org/0000-0001-7789-8945
Yanzhou JiangDepartment of Orthopaedics, Weifang City Hanting People's Hospital, Weifang 261100, China.ORCID https://orcid.org/0000-0002-5864-2263
Haixia QianDepartment of Cardiovascular Medicine, Weifang City Hanting People's Hospital, Weifang 261100, China.ORCID https://orcid.org/0000-0002-4647-1946
Xiaomin LiuDepartment of Orthopaedics, Weifang City Hanting People's Hospital, Weifang 261100, China.ORCID https://orcid.org/0000-0002-3279-8665
Liguo MiDepartment of Anatomy, Hebei Medical University, Shijiazhuang 050017, China.ORCID https://orcid.org/0000-0002-6858-2989
Weifang People's Hospital · CNHebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the effect of cardiac troponin I-interacting kinase (

Indexed as

ApoptosisAnimalsbcl-2-Associated X ProteinCaspase 3Cell LineDisease Models, AnimalGene SilencingHeart FailureLipopolysaccharidesMyocardiumProtein-Tyrosine KinasesRatsRNA, MessengerSepsisTransfectionUp-RegulationBax protein, ratbcl-2-Associated X ProteinCaspase 3LipopolysaccharidesProtein-Tyrosine KinasesRNA, MessengerTNNI3K protein, rat

Identifiers

PMID34136567
PMCPMC8175134
OpenAlexW3169320969

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.