ArticleFrontiers in cell and developmental biology2021
Genetic Screening Revealed Latent Keratoconus in Asymptomatic Individuals.
Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Proteomic Analysis Provides Insights Into PPIP5K2 Function and Its Impact on Corneal Energy Metabolism.Investigative ophthalmology & visual science · 2025Article
- Genetics of Keratoconus: A Comprehensive Review.Genes · 2025Review
- Subclinical parents assist in the detection of genetic variants in keratoconus by trio-based whole-exome sequencing.Molecular vision · 2025Article
- Multi-modal imaging for the detection of early keratoconus: a narrative review.Eye and vision (London, England) · 2024Review
- Exploring the causal relationship between body mass index and keratoconus: a Mendelian randomization study.Frontiers in medicine · 2024Article
- Increased inflammatory mediators in the ocular surface tissue in keratoconus.Molecular vision · 2024Article
- Association between Polymorphism rs61876744 inGenes · 2023Article
- Clinical and genetic analysisFrontiers in genetics · 2023Article
- Keratoconus Diagnosis and Treatment: Recent Advances and Future Directions.Clinical ophthalmology (Auckland, N.Z.) · 2023Review
- Biochemical and molecular alterations and potential clinical applications of biomarkers in keratoconus.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo adopt molecular screening in asymptomatic individuals at high risk of developing keratoconus as a combinative approach to prevent subclinical patients from post-refractive surgery progressive corneal ectasia.
methodsIn this study, 79 Chinese and nine Greek families with keratoconus were recruited, including 91 patients with clinically diagnosed keratoconus as well as their asymptomatic but assumptive high-risk first-degree relatives based on underlying genetic factor. Mutational screening of
resultsFive variants in
conclusionsVariants of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.