Evidence map›Paper›PMID 34136400›Full record

ArticleFrontiers in oncology2021

Survival Outcomes and Treatment Decision by Human Papillomavirus Status Among Patients With Stage IVC Head and Neck Squamous Cell Carcinoma.

Ping Zhou, Yi-Feng Yu, Chen-Lu Lian, Jun Wang, Ren-Gong Zhuo, San-Gang Wu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  7. lncRNABiomedicines · 2025
    Article
  8. Article
  9. Article
  10. Adjuvant (chemo)radiotherapy for patients with head and neck cancer: can comorbidity risk scores predict outcome?Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024
    Article
  11. Article
  12. Diagnostic Delay in HPV-Related Oropharyngeal Squamous Cell Carcinoma.International archives of otorhinolaryngology · 2024
    Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ping ZhouDepartment of Radiation Oncology, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Yi-Feng YuDepartment of Radiation Oncology, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Chen-Lu LianDepartment of Radiation Oncology, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Jun WangDepartment of Radiation Oncology, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Ren-Gong ZhuoXiamen Key Laboratory of Chiral Drugs, Medical College, Xiamen University, Xiamen, China.
San-Gang WuDepartment of Radiation Oncology, The First Affiliated Hospital of Xiamen University, Xiamen, China.
First Affiliated Hospital of Xiamen University · CNXiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the influence of human papillomavirus (HPV) status on survival outcomes and treatment decisions for patients with

methodsPatients initially diagnosed with

resultsWe identified 303 patients who received chemotherapy in this study, including 52.5% of them had HPV-positive disease. HPV-positive HNSCC had better HNCSS (P

conclusionsApproximately half of the stage IVC HNSCC patients are HPV-related. The presence of HPV infection appears to be strongly associated with the survival outcome in patients with

Indexed as

decision-makinghead and neck squamous cell carcinomahuman papillomavirusprognosisradiotherapy

Identifiers

PMID34136400
PMCPMC8201515
OpenAlexW3169475650

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.