Evidence map›Paper›PMID 34136395›Full record

ArticleFrontiers in oncology2021

Aberrant Expression of PAFAH1B3 Affects Proliferation and Apoptosis in Osteosarcoma.

Jian Fan, Yi Yang, Ji-Kui Qian, Xin Zhang, Jia-Qing Ji, Li Zhang, Shan-Zhu Li, Feng Yuan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jian FanDepartment of Orthopedics, Tongji Hospital, Tongji University, Shanghai, China.
Yi YangDepartment of Orthopedics, Tongji Hospital, Tongji University, Shanghai, China.
Ji-Kui QianDepartment of Orthopedics, Tongji Hospital, Tongji University, Shanghai, China.
Xin ZhangDepartment of Orthopedics, Tongji Hospital, Tongji University, Shanghai, China.
Jia-Qing JiDepartment of Orthopedics, Tongji Hospital, Tongji University, Shanghai, China.
Li ZhangDepartment of Orthopedics, Tongji Hospital, Tongji University, Shanghai, China.
Shan-Zhu LiDepartment of Orthopedics, Tongji Hospital, Tongji University, Shanghai, China.
Feng YuanDepartment of Orthopedics, Tongji Hospital, Tongji University, Shanghai, China.
Tongji Hospital · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma is a major malignant tumor of bone and soft tissue, which is presenting with early metastasis and a high mortality rate. Platelet activating factor acetylhydrolase 1B3 (PAFAH1B3), a cancer-relevant molecular, was found to play a vital role in tumorigenesis and aggressiveness in several cancer types. However, the roles and the regulating mechanisms of PAFAH1B3 in osteosarcoma progression remain unclear. PAFAH1B3 expression was detected by immunohistochemistry in 83 osteosarcoma tissues and 44 paired adjacent normal bone tissues.

Indexed as

apoptosiscell proliferationosteosarcomaplatelet activating factor acetylhydrolase 1B3therapeutic target

Identifiers

PMID34136395
PMCPMC8201501
OpenAlexW3172828116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.