Evidence map›Paper›PMID 34136262›Full record

ArticleRespirology case reports2021

Fatal cytomegalovirus pneumonia in a critically ill patient with COVID-19.

Saori Amiya, Haruhiko Hirata, Takayuki Shiroyama, Yuichi Adachi, Takayuki Niitsu, Yoshimi Noda, Takatoshi Enomoto, Reina Hara, Kiyoharu Fukushima, Yasuhiko Suga and 5 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Respirology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Cytomegalovirus reactivation in patients diagnosed with severe COVID-19: A point prevalence study in a general hospital.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2023
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  10. Cytomegalovirus Coinfection in Critically Ill Patients with Novel Coronavirus-2019 Disease: Pathogens or Spectators?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Saori AmiyaDepartment of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine Osaka Japan.
Haruhiko HirataDepartment of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine Osaka Japan.
Takayuki ShiroyamaDepartment of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine Osaka Japan.ORCID https://orcid.org/0000-0002-2816-9428
Yuichi AdachiDepartment of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine Osaka Japan.
Takayuki NiitsuDepartment of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine Osaka Japan.
Yoshimi NodaDepartment of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine Osaka Japan.
Takatoshi EnomotoDepartment of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine Osaka Japan.
Reina HaraDepartment of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine Osaka Japan.
Kiyoharu FukushimaDepartment of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine Osaka Japan.
Yasuhiko SugaDepartment of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine Osaka Japan.
Kotaro MiyakeDepartment of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine Osaka Japan.
Moe KoideDepartment of Anesthesiology and Intensive Care Medicine Osaka University Graduate School of Medicine Osaka Japan.
Akinori UchiyamaDepartment of Anesthesiology and Intensive Care Medicine Osaka University Graduate School of Medicine Osaka Japan.
Yoshito TakedaDepartment of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine Osaka Japan.
Atsushi KumanogohDepartment of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine Osaka Japan.
Osaka City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) can cause severe lymphopenia and respiratory failure requiring prolonged invasive mechanical ventilation (MV). COVID-19 patients with severe lymphopenia or respiratory failure are at risk of developing secondary infections. Here, we present the needle autopsy findings of a critically ill patient with COVID-19 who required reintubation and prolonged MV, and eventually died of secondary cytomegalovirus (CMV) pneumonia. This case highlights the potential risk of long-term steroid use and the need for routine monitoring for CMV infection in critically ill patients with COVID-19.

Indexed as

Co‐infectioncorticosteroid therapyCOVID‐19cytomegalovirus pneumonialymphopenia

Identifiers

PMID34136262
PMCPMC8185623
OpenAlexW3167692242

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.