Evidence map›Paper›PMID 34136239›Full record

ArticleClinical case reports2021

Isolated adrenocorticotropin deficiency induced by pembrolizumab for hypopharyngeal cancer: A case report.

Koichiro Yamamoto, Kazuki Tokumasu, Kosuke Oka, Kou Hasegawa, Fumio Otsuka

Open access · goldAbstract read
In one paragraph

Article in Clinical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Koichiro YamamotoDepartment of General Medicine Dentistry and Pharmaceutical Sciences Okayama University Graduate School of Medicine Okayama Japan.ORCID https://orcid.org/0000-0001-9571-1646
Kazuki TokumasuDepartment of General Medicine Dentistry and Pharmaceutical Sciences Okayama University Graduate School of Medicine Okayama Japan.
Kosuke OkaDepartment of General Medicine Dentistry and Pharmaceutical Sciences Okayama University Graduate School of Medicine Okayama Japan.
Kou HasegawaDepartment of General Medicine Dentistry and Pharmaceutical Sciences Okayama University Graduate School of Medicine Okayama Japan.
Fumio OtsukaDepartment of General Medicine Dentistry and Pharmaceutical Sciences Okayama University Graduate School of Medicine Okayama Japan.ORCID https://orcid.org/0000-0001-7014-9095
Okayama University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of isolated adrenocorticotropin deficiency caused by pembrolizumab. This condition can be fatal, but its rarity causes under-recognition. Oncologists should pay attention to adrenal insufficiency due to pembrolizumab.

Indexed as

adrenal insufficiencyfever of unknown originhypophysitisimmune‐related adverse eventsprogrammed cell death 1 protein inhibitor

Identifiers

PMID34136239
PMCPMC8190675
OpenAlexW3170107577

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.