Evidence map›Paper›PMID 34136235›Full record

ArticleClinical case reports2021

Crizotinib-associated renal cyst development may be associated with prolonged progression-free survival in patients with

Nathaniel E Wiest, Katherine S Tzou, Matthew T Olson, Steven M Herchko, Essa M Bajalia, David D Thiel, Yanyan Lou, Yujie Zhao, Rami Manochakian

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Nathaniel E WiestDepartment of Internal Medicine Mayo Clinic Florida Jacksonville FL USA.ORCID https://orcid.org/0000-0002-6211-2716
Katherine S TzouDepartment of Radiation Oncology Mayo Clinic Florida Jacksonville FL USA.
Matthew T OlsonRoche Diagnostics Tucson AZ USA.
Steven M HerchkoDepartment of Radiation Oncology Mayo Clinic Florida Jacksonville FL USA.
Essa M BajaliaDepartment of Urology Mayo Clinic Florida Jacksonville FL USA.
David D ThielDepartment of Urology Mayo Clinic Florida Jacksonville FL USA.
Yanyan LouDivision of Hematology/Oncology Department of Medicine Mayo Clinic Florida Jacksonville FL USA.
Yujie ZhaoDivision of Hematology/Oncology Department of Medicine Mayo Clinic Florida Jacksonville FL USA.
Rami ManochakianDivision of Hematology/Oncology Department of Medicine Mayo Clinic Florida Jacksonville FL USA.
Jacksonville College · USRoche (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-small cell lung cancer patients with anaplastic lymphoma kinase or c-ros oncogene 1 mutations who are treated with the tyrosine kinase inhibitor crizotinib rarely develop crizotinib-associated renal cysts (CARCs). Here, we present a case report and review of the literature supporting the hypothesis that CARCs may correlate positively with progression-free survival.

Indexed as

ALK positivecrizotinibnon‐small‐cell lung cancerprogression‐free survivalrenal cysts

Identifiers

PMID34136235
PMCPMC8190584
OpenAlexW3169538538

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.