ReviewAnnals of medicine and surgery (2012)2021
Role of platelet indices as a biomarker for the diagnosis of acute appendicitis and as a predictor of complicated appendicitis: A meta-analysis.
Review in Annals of medicine and surgery (2012), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Research on the construction of an artificial intelligence model for the early diagnosis of pediatric acute appendicitis: a single-center retrospective study based on complete blood count.BMC pediatrics · 2026Article
- A Hybrid Model with Quantum Feature Map Based on CNN and Vision Transformer for Clinical Support in Diagnosis of Acute Appendicitis.Biomedicines · 2026Article
- Hyperbilirubinemia as a Marker for Complicated Acute Appendicitis: A Systematic Review.Cureus · 2025Review
- Mean Platelet Volume as an Emerging Biomarker for Diagnosing Acute Appendicitis: A Retrospective Study.Cureus · 2024Article
- The role of IL-6, thiol-disulfide homeostasis, and inflammatory biomarkers in the prediction of acute appendicitis in children: a controlled study.Pediatric surgery international · 2023Article
- Application and curative effect of laparoscopic purse-string sutures in the treatment of adult acute complicated appendicitis.BMC surgery · 2023Article
- The Value of Complete Blood Count Parameters in Predicting Complicated Acute Appendicitis; a Prognostic Accuracy Study.Archives of academic emergency medicine · 2023Article
- Diagnostic value of serum signal peptide-CUB-EGF-like domain-containing protein 1 levels in patients with acute appendicitis.Revista da Associacao Medica Brasileira (1992) · 2023Article
- The relationship between platelet distribution width and new-onset cardiovascular disease events in patients with peritoneal dialysis.Renal failure · 2022Article
- Mean Platelet Volume in the Diagnosis of Acute Appendicitis in the Pediatric Population: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2022Review
- Neutrophil to Lymphocyte Ratio (NLR) as an Easily Accessible Parameter for Monitoring Tacrolimus Overdose after Heart Transplantation-Experimental Study.Diagnostics (Basel, Switzerland) · 2021Article
- Predictive Value of Red Blood Cell Distribution Width, Mean Platelet Volume and Platelet Distribution Width in Children with Acute Appendicitis.Children (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAcute appendicitis is one of the most common surgical emergencies worldwide. Clinical scoring system systems have been developed to diagnose acute appendicitis, but insufficient to predict the complication. The amount of serum biomarkers elevates in response to acute inflammation, which could be beneficial for diagnostic tools. Accordingly, a meta-analysis was conducted to evaluate the efficacy of platelet indices, including mean platelet volume (MVP) and platelet distribution width (PDW) as potential biomarkers for the diagnosis of a diagnosis of acute appendicitis. MATERIAL AND
methodsThe dataset was defined by searching for articles published until December 2020 from PubMed, EMBASE, Google Scholar and the Cochrane database. The meta-analysis was performed using Review Manager Software version 5.4.1.
resultsThe final analysis was made from 9 studies, including 3124 patients. The results demonstrated that lower MPV values was significantly associated with acute appendicitis (odds ratio (OR) = 0.81, 95% confidence interval (CI) = -1.51 to -0.11, P = 0.02), but not associated with complicated appendicitis by comparing it with the control (OR = -0.13,95% CI = -0.33 to -0.07, P = 0.19) and non-complicated appendicitis groups (OR = -0.13,95% CI = -0.30 to -0.04, P = 0.14). The present study failed to demonstrate the diagnostic value of PDW for the prediction of appendicitis and its complication.
conclusionThe results of the meta-analysis strongly indicate that a lower MVP values could function as a marker for predicting the acute appendicitis.
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