Evidence map›Paper›PMID 34136150›Full record

ArticleFood science & nutrition2021

Accumulating evidence to support the safe and efficacious use of a proprietary blend of capsaicinoids in mediating risk factors for obesity.

Javahar Kohli Mariwala, Deshanie Rai, Muralidhara Padigaru, Abhijeet Ashok Morde, Ewa Maddox, Samar Maalouf, Kayla Smith, John P Vanden Heuvel

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Nutrients · 2026
    Article
  2. Review
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Javahar Kohli MariwalaOmniActive Health Technologies, Inc. Morristown NJ USA.
Deshanie RaiOmniActive Health Technologies, Inc. Morristown NJ USA.
Muralidhara PadigaruOmniActive Health Technologies, Inc. Morristown NJ USA.
Abhijeet Ashok MordeOmniActive Health Technologies, Inc. Morristown NJ USA.
Ewa MaddoxINDIGO Biosciences, Inc. State College PA USA.
Samar MaaloufINDIGO Biosciences, Inc. State College PA USA.
Kayla SmithINDIGO Biosciences, Inc. State College PA USA.
John P Vanden HeuvelINDIGO Biosciences, Inc. State College PA USA.ORCID https://orcid.org/0000-0002-3350-2037
OmniActive Health Technologies (United States) · USQ-State Biosciences (United States) · USPennsylvania State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is a significant public health concern, and finding safe and effective means for combating this condition is needed. This study investigates the safety and efficacy of supplementation of a blend of capsaicinoids on weight gain, fat mass, and blood chemistry in a high-fat diet (HFD) model of obesity in mice and on adipocyte differentiation and gene expression in 3T3-L1 preadipocytes. High-fat diet (HFD)-fed mice were treated with a proprietary capsaicinoid concentrate (Capsimax

Indexed as

adipogenesisCapsaicingene expressionobesitythermogenesis

Identifiers

PMID34136150
PMCPMC8194937
OpenAlexW3157297119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.