Evidence map›Paper›PMID 34135993›Full record

ReviewEuropean cardiology2021

Direct Oral Anticoagulants in Asian Patients with Atrial Fibrillation: Consensus Recommendations by the Asian Pacific Society of Cardiology on Strategies for Thrombotic and Bleeding Risk Management.

Daniel Tt Chong, Felicita Andreotti, Peter Verhamme, Jamshed Dalal, Noppacharn Uaprasert, Chun-Chieh Wang, Young Keun On, Yi-Heng Li, Jun Jiang, Koji Hasegawa and 10 more

Open access · goldAbstract readReview
In one paragraph

Review in European cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Prevention of nNon-Vitamin K Oral Anticoagulants-Related Gastrointestinal Bleeding With Acid Suppressants: A Systematic Review and Meta-Analysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Pooled it
  3. Trial
  4. Article
  5. Article
  6. 2025 Thai guideline for the diagnosis and management of atrial fibrillation.Asian biomedicine : research, reviews and news · 2025
    Article
  7. Article
  8. Observational
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 17 institutions in 12 countries.

Daniel Tt ChongNational Heart Centre Singapore.
Felicita AndreottiFondazione Policlinico Universitario A Gemelli IRCCS Rome, Italy.
Peter VerhammeUniversity of Leuven Leuven, Belgium.
Jamshed DalalKokilaben Hospital Mumbai, India.
Noppacharn UaprasertChulalongkorn University and King Chulalongkorn Memorial Hospital Bangkok, Thailand.
Chun-Chieh WangChang Gung Memorial Hospital, Linkou and Chang Gung University College of Medicine Taoyuan City, Taiwan.
Young Keun OnSamsung Medical Center, Sungkyunkwan University School of Medicine Seoul, South Korea.
Yi-Heng LiNational Cheng King University Hospital Taiwan.
Jun JiangSecond Affiliated Hospital Zhejiang University School of Medicine Zhejiang, China.
Koji HasegawaTranslational Research, National Hospital Organization Kyoto Medical Center Kyoto, Japan.
Khalid AlmutiCleveland Clinic Abu Dhabi United Arab Emirates.
Rong BaiBeijing Anzhen Hospital, Capital Medical University Beijing, China.
Sidney Th LoLiverpool Hospital Sydney, Australia.
Rungroj KrittayaphongSiriraj Hospital, Mahidol University Bangkok, Thailand.
Lai Heng LeeSingapore General Hospital Singapore.
David Kl QuekPantai Hospital Kuala Lumpur Kuala Lumpur, Malaysia.
Sofian JoharRipas Hospital Brunei.
Swee-Chong SeowNational University Hospital Singapore.
Christopher J HammettRoyal Brisbane and Women's Hospital Brisbane, Australia.
Jack Wc TanNational Heart Centre Singapore.
Hospital Kuala Lumpur · MYNational Heart Centre Singapore · SGCapital Medical University · CNChang Gung University · TWChulalongkorn University · THIstituti di Ricovero e Cura a Carattere Scientifico · ITKokilaben Dhirubhai Ambani Hospital · INKU Leuven · BEKyoto Medical Center · JPLiverpool Hospital · AUNational Cheng Kung University Hospital · TWNational University Hospital · SGRaja Isteri Pengiran Anak Saleha Hospital · BNRoyal Brisbane and Women's Hospital · AUSamsung Medical Center · KRSecond Affiliated Hospital of Zhejiang University · CNSiriraj Hospital · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The disease burden of AF is greater in Asia-Pacific than other areas of the world. Direct oral anticoagulants (DOACs) have emerged as effective alternatives to vitamin K antagonists (VKA) for preventing thromboembolic events in patients with AF. The Asian Pacific Society of Cardiology developed this consensus statement to guide physicians in the management of AF in Asian populations. Statements were developed by an expert consensus panel who reviewed the available data from patients in Asia-Pacific. Consensus statements were developed then put to an online vote. The resulting 17 statements provide guidance on the assessment of stroke risk of AF patients in the region, the appropriate use of DOACs in these patients, as well as the concomitant use of DOACs and antiplatelets, and the transition to DOACs from VKAs and vice versa. The periprocedural management of patients on DOAC therapy and the management of patients with bleeding while on DOACs are also discussed.

Indexed as

AFAsiableedingconsensushaemostasisnon-vitamin K antagonist oral anticoagulantsvitamin K antagonist

Identifiers

PMID34135993
PMCPMC8201470
OpenAlexW3167200724

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.