ArticleInternational journal of endocrinology2021
Correlation between Thyroid Homeostasis and Obesity in Subclinical Hypothyroidism: Community-Based Cross-Sectional Research.
Article in International journal of endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Waist circumference versus BMI: A cross-sectional study comparing Cardiometabolic Risk association in the Nepalese Population.PloS one · 2026Article
- Incidence of Subclinical Hypothyroidism in Obese Adults and Its Metabolic Implications: A Prospective Cohort Study.Cureus · 2025Article
- Correlation between thyroid hormone sensitivity and diabetic peripheral neuropathy in euthyroid patients with type 2 diabetes mellitus.Scientific reports · 2024Article
- Relationship between Thyroid Feedback Quantile-based Index and cardiovascular diseases in a population with normal thyroid function: Evidence from the National Health and Nutrition Examination Survey 2007-2012.Clinical cardiology · 2024Article
- Impaired Sensitivity to Thyroid Hormones is Associated with Central Obesity in Euthyroid Type 2 Diabetes Mellitus Patients with Overweight and Obesity.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Impaired Sensitivity to Thyroid Hormones Is Associated With the Change of Abdominal Fat in Euthyroid Type 2 Diabetes Patients: A Retrospective Cohort Study.Journal of diabetes research · 2024Article
- Thyroid Hormone Resistance Syndrome: From Molecular Mechanisms to Its Potential Contribution to Hypertension.Cureus · 2023Review
- Prevalence of dyslipidemia and the association with levels of TSH and T4 hormones among patients in south region of Jordan.Journal of medical biochemistry · 2023Article
- Pituitary T1 signal intensity at magnetic resonance imaging is reduced in patients with obesity: results from the CHIASM study.International journal of obesity (2005) · 2023Review
- Association of impaired sensitivity to thyroid hormones with hyperuricemia through obesity in the euthyroid population.Journal of translational medicine · 2023Article
- Association between sensitivity to thyroid hormone indices and the risk of osteoarthritis: an NHANES study.European journal of medical research · 2022Article
- Increased Central and Peripheral Thyroid Resistance Indices During the First Half of Gestation Were Associated With Lowered Risk of Gestational Diabetes-Analyses Based on Huizhou Birth Cohort in South China.Frontiers in endocrinology · 2022Article
- Association of Thyroid Function Test Values with Prepregnancy Body Mass Index and Gestational Weight Gain: A Systematic Review of Literature Reviews.Iranian journal of nursing and midwifery researchReview
Corrections and comments
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Authors and funding
17 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIt remains unknown whether obesity has an effect on the pituitary-thyroid feedback control axis in subclinical hypothyroidism (SCH). We aimed to investigate the association of thyroid homeostasis with obesity in a SCH population.
methodsOur study consisted of a community-based and cross-sectional study from the Epidemiological Survey of Thyroid Diseases in Fujian Province, China. A total of 193 subjects with SCH (90 males and 103 females) without a history of treatment of thyroid disease, such as surgery, radiation, and thyroid hormone or antithyroid medication, were included in the present study. Indices of obesity, including body mass index (BMI), waist circumference (WC), and waist-height ratio (WHtR) were measured.
resultsOur results showed that the secretory capacity of the thyroid gland (SPINA-GT) and Jostel's thyrotropin index (TSHI) were negatively correlated with BMI, WC, and WHtR, whereas the reciprocal of the thyrotroph thyroid hormone resistance index (TTSI-1) was positively correlated with BMI (all
conclusionsThese results suggest that low levels of thyroid homeostasis indexes may be associated with overall obesity in SCH, rather than central adiposity.
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Registered trials
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