Evidence map›Paper›PMID 34135902›Full record

ArticleFrontiers in immunology2021

A Component-Resolved Therapeutic Vaccine for Cockroach Allergy Made of Per a 9 and Transforming Growth Factor-β Homologue, an Immunosuppressive Protein of

Pannathee Prangtaworn, Kodchakorn Mahasongkram, Atiporn Saeung, Urai Chaisri, Watee Seesuay, Onrapak Reamtong, Anchalee Tungtrongchitr, Wanpen Chaicumpa, Nitat Sookrung

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Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pannathee PrangtawornGraduate Program in Immunology, Department of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Kodchakorn MahasongkramCenter of Research Excellence on Therapeutic Proteins and Antibody Engineering, Department of Parasitology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Atiporn SaeungDepartment of Parasitology, Faculty of Medicine, Chiang-Mai University, Chiang Mai, Thailand.
Urai ChaisriDepartment of Tropical Pathology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Watee SeesuayCenter of Research Excellence on Therapeutic Proteins and Antibody Engineering, Department of Parasitology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Onrapak ReamtongDepartment of Tropical Molecular Biology and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Anchalee TungtrongchitrCenter of Research Excellence on Therapeutic Proteins and Antibody Engineering, Department of Parasitology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Wanpen ChaicumpaCenter of Research Excellence on Therapeutic Proteins and Antibody Engineering, Department of Parasitology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Nitat SookrungCenter of Research Excellence on Therapeutic Proteins and Antibody Engineering, Department of Parasitology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergen-specific-immunotherapy (ASIT) can cause long-term resolution of allergic diseases, reduces drug use and chances of new allergen sensitization. Nevertheless, therapeutic vaccine and data on ASIT efficacy for cockroach (CR) allergy are relatively scarce. In this study, efficacy and mechanism of a novel intranasal vaccine consisting of liposome (L)-entrapped mixture of American CR (

Indexed as

Administration, IntranasalAllergensAnimalsArginine KinaseBrugia malayiDendritic CellsDesensitization, ImmunologicDisease Models, AnimalHypersensitivityImmunoglobulin EImmunoglobulin GImmunosuppressive AgentsInsect ProteinsLiposomesMaleMiceAllergensArginine KinaseImmunoglobulin EImmunoglobulin GImmunosuppressive AgentsInsect ProteinsLiposomesPer a 9 allergen, Periplaneta americanaTransforming Growth Factor betaVaccinesBrugia malayicockroach allergyimmunotherapyPer a 9Periplaneta americanatherapeutic vaccinetransforming growth factor-beta homologue

Identifiers

PMID34135902
PMCPMC8201610

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.