Evidence map›Paper›PMID 34135893›Full record

ArticleFrontiers in immunology2021

MiR-154-5p-MCP1 Axis Regulates Allergic Inflammation by Mediating Cellular Interactions.

Misun Kim, Hyein Jo, Yoojung Kwon, Myeong Seon Jeong, Hyun Suk Jung, Youngmi Kim, Dooil Jeoung

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Mast cell-derived extracellular vesicles in lung diseases: roles in pulmonary inflammation, immune regulation, and microenvironmental remodeling.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
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  10. Specific microRNA Signature Kinetics inInternational journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Misun KimDepartment of Biochemistry, Kangwon National University, Chuncheon, South Korea.
Hyein JoDepartment of Biochemistry, Kangwon National University, Chuncheon, South Korea.
Yoojung KwonDepartment of Biochemistry, Kangwon National University, Chuncheon, South Korea.
Myeong Seon JeongDepartment of Biochemistry, Kangwon National University, Chuncheon, South Korea.
Hyun Suk JungDepartment of Biochemistry, Kangwon National University, Chuncheon, South Korea.
Youngmi KimInstitute of New Frontier Research, College of Medicine, Hallym University, Chuncheon, South Korea.
Dooil JeoungDepartment of Biochemistry, Kangwon National University, Chuncheon, South Korea.
Kangwon National University · KRHallym University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a previous study, we have demonstrated that p62, a selective receptor of autophagy, can regulate allergic inflammation. In the present study, microRNA array analysis showed that miR-154-5p was increased by antigen (DNP-HSA) in a p62-dependent manner in rat basophilic leukemia cells (RBL2H3). NF-kB directly increased the expression of miR-154-5p. miR-154-5p mediated

Indexed as

Cell CommunicationGene Expression RegulationRNA InterferenceAnaphylaxisAnimalsAntigensChemokine CCL2Disease Models, AnimalExosomesFemaleHypersensitivityMiceMicroRNAsSkinTreatment OutcomeAntigensCcl2 protein, mouseChemokine CCL2MicroRNAsMIRN154 microRNA, mouseallergic inflammationcellular interactionsexosomesMCP1miR-154-5p

Identifiers

PMID34135893
PMCPMC8201518
OpenAlexW3169458869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.