Evidence map›Paper›PMID 34135888›Full record

ReviewFrontiers in immunology2021

Schistosomiasis Drug Discovery in the Era of Automation and Artificial Intelligence.

José T Moreira-Filho, Arthur C Silva, Rafael F Dantas, Barbara F Gomes, Lauro R Souza Neto, Jose Brandao-Neto, Raymond J Owens, Nicholas Furnham, Bruno J Neves, Floriano P Silva-Junior and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Plant-Derived Terpenes as Emerging Therapeutics Against Schistosomiasis.International journal of molecular sciences · 2026
    Review
  2. Article
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  4. Molecules (Basel, Switzerland) · 2025
    Article
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  6. Review
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

José T Moreira-FilhoLabMol - Laboratory for Molecular Modeling and Drug Design, Faculdade de Farmácia, Universidade Federal de Goiás - UFG, Goiânia, Brazil.
Arthur C SilvaLabMol - Laboratory for Molecular Modeling and Drug Design, Faculdade de Farmácia, Universidade Federal de Goiás - UFG, Goiânia, Brazil.
Rafael F DantasLaBECFar - Laboratório de Bioquímica Experimental e Computacional de Fármacos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Barbara F GomesLaBECFar - Laboratório de Bioquímica Experimental e Computacional de Fármacos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Lauro R Souza NetoLaBECFar - Laboratório de Bioquímica Experimental e Computacional de Fármacos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Jose Brandao-NetoDiamond Light Source Ltd., Didcot, United Kingdom.
Raymond J OwensThe Rosalind Franklin Institute, Harwell, United Kingdom.
Nicholas FurnhamDepartment of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Bruno J NevesLabMol - Laboratory for Molecular Modeling and Drug Design, Faculdade de Farmácia, Universidade Federal de Goiás - UFG, Goiânia, Brazil.
Floriano P Silva-JuniorLaBECFar - Laboratório de Bioquímica Experimental e Computacional de Fármacos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Carolina H AndradeLabMol - Laboratory for Molecular Modeling and Drug Design, Faculdade de Farmácia, Universidade Federal de Goiás - UFG, Goiânia, Brazil.
Fundação Oswaldo Cruz · BRUniversidade Federal de Goiás · BRLondon School of Hygiene & Tropical Medicine · GBResearch Complex at Harwell · GBRosalind Franklin Institute · GB

Funding

Medical Research Council MR/M026221/1Medical Research Council MR/T000171/1
6 · The paper itself

Abstract

Schistosomiasis is a parasitic disease caused by trematode worms of the genus

Indexed as

Artificial IntelligenceSchistosomicidesAnimalsDrug DiscoveryHumansSchistosomaSchistosomiasisSchistosomicidesartificial intelligencedrug discoveryfragment-based drug discoveryphenotypic screeningschistosomiasistarget-based screening

Identifiers

PMID34135888
PMCPMC8203334
OpenAlexW3169910019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.