Evidence map›Paper›PMID 34135672›Full record

ArticleSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2021

Relationship between different anti-rheumatic drug therapies and complementary and alternative medicine in patients with rheumatoid arthritis: an interview based cross-sectional study.

Haya M Almalag, Aseel M Almuhareb, Aya A Alsharafi, Tariq M Alhawassi, Ahmed A Alghamdi, Hussain Alarfaj, Mohammed A Omair, Bedor A Alomari, Maysoon S Alblowi, Hanan H Abouzaid and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Haya M AlmalagDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Aseel M AlmuharebDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Aya A AlsharafiDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Tariq M AlhawassiDepartment of Clinical Pharmacy and Medication Safety Research Chair, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Ahmed A AlghamdiDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Hussain AlarfajRheumatology Unit, Department of Medicine, King Saud University Medical City, Riyadh, Saudi Arabia.
Mohammed A OmairRheumatology Unit, Department of Medicine, King Saud University Medical City, Riyadh, Saudi Arabia.
Bedor A AlomariRheumatology Clinical Pharmacist, Department of Pharmaceutical Service, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Maysoon S AlblowiRheumatology Unit, Department of Medicine, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Hanan H AbouzaidDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Abdurhman S AlarfajRheumatology Unit, Department of Medicine, King Saud University Medical City, Riyadh, Saudi Arabia.
King Saud University · SAKing Saud Medical City · SARiyadh Armed Forces Hospital · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe use of complementary and alternative medicine (CAM) by patients with rheumatoid arthritis (RA) is highly prevalent. The relationship of these remedies with disease therapy are not fully studied. We aimed to explore the relationship between different anti-rheumatic drug therapy and CAM use in RA patients.

methodsThe study used an interview-based cross-sectional survey in two major referral centres in Riyadh, Saudi Arabia. Patients were adults with confirmed RA that attended rheumatology clinics. Information on the utilization of CAM, RA duration, drug therapy, and laboratory parameters were obtained. Descriptive statistics as well as adjusted odds ratio using bivariate logistic regression were used to explore the different factors related to CAM use, including drug therapy.

resultsA total of 438 adult patients with RA were included. The mean (±SD) age of the patients was 49 (±15.0) years. The majority were women 393 (89.7%). Two hundred and ninety-two patients (66.7%) had used CAM. The CAM users who had a longer disease duration (AOR 1.041 [95% CI: 1.011, 1.073];

conclusionCAM use is prevalent in patients with RA. Understanding patients and disease related factors associated with higher use of CAM is warranted to improve RA management and provide more rational use of these remedies.

Indexed as

Anti-rheumatic therapiesCAM, complementary and alternative medicineCAM practicesChronic illnessDisease activityHAQ, health assessment questionnaireHCQ, hydroxychloroquineLEF, leflunomideMTX, MethotrexatePatient safetyRA, rheumatoid arthritisRheumatoid arthritisSSZ, sulfasalazineTNFi, tumour necrosis factor inhibitor

Identifiers

PMID34135672
PMCPMC8180625
OpenAlexW3157263948

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.