ArticleNature2021
Geometry of abstract learned knowledge in the hippocampus.
Abstract read
In one paragraph
Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers.
0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
155 citing papers in PubMed.
- Representational learning by optimization of neural manifolds in an olfactory memory network.Nature neuroscience · 2026Article
- Offline generative network reconfiguration guides insight-like accelerated learning by assimilation into schema in rats.Nature communications · 2026Article
- Cerebellar microcircuits enable robust evidence-based decisions through cortico-cerebellar coupling.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Goal-directed hippocampal theta sweeps during memory-guided navigation.Nature neuroscience · 2026Article
- Article
- Neural dynamics underlying minute-timescale persistent behaviour in the human brain.Nature human behaviour · 2026Article
- Food, mammals, & countries: Stimuli, their pairwise similarities, and MDS dimension values for modeling judgment, categorization, and memory in three real-world domains.Behavior research methods · 2026Article
- A deep reinforcement learning account of competition and integration of visual and goal vector signals for spatial navigation.Scientific reports · 2026Article
- Generative AI as a transformational logic for cognitive neuroscience.Communications biology · 2026Review
- Transformations of the spatial activity manifold convey aversive information in CA3.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Primary cilia and neural computation.Journal of biomedical science · 2026Review
- GATE: Adaptive learning with working memory by information gating in multi-lamellar hippocampal formation.PLoS computational biology · 2026Article
- The hippocampus as a small-world cognitive map.bioRxiv : the preprint server for biology · 2026Article
- Computational neural dynamics of goal-directed visual attention in macaques.Science advances · 2026Article
- Distinct CA3 inputs differentially shape the learning-dependent evolution of right CA1 spatial maps.Nature communications · 2026Article
- Sleep strengthens successor representations of learned sequences in humans.PLoS biology · 2026Article
- Neural circuit models for evidence accumulation through choice-selective sequences.Nature communications · 2026Article
- Neural geometry in the human hippocampus enables generalization across spatial position and gaze.ArXiv · 2026Article
- Contextual inference through flexible integration of environmental features and behavioural outcomes.PLoS computational biology · 2026Article
- Neural population geometry and optimal coding of tasks with shared latent structure.Nature neuroscience · 2026Article
95 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
10 authors.
Edward H Nieh *Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0003-2154-6224
Manuel Schottdorf *Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0002-5468-4255
Nicolas W FreemanPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Ryan J LowPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Sam LewallenPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Sue Ann KoayPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0002-9648-2475
Lucas PintoPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0002-0471-9317
Jeffrey L GauthierPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0002-0509-8532
Carlos D BrodyPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA. brody@princeton.edu.ORCID http://orcid.org/0000-0002-4201-561X
David W TankPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA. dwtank@princeton.edu.ORCID http://orcid.org/0000-0002-9423-4267
Funding
Subcortical Neural Coding and DynamicsU19NS104648 · NINDS · PRINCETON UNIVERSITY · PI BRODY, CARLOS D · 2017 to 2021
$15.3MMechanisms of neural circuit dynamics in working memoryU01NS090541 · NINDS · PRINCETON UNIVERSITY · PI BIALEK, WILLIAM, BRODY, CARLOS D · 2014 to 2016
$3.1MCharacterizing the underlying population code to understand the functional organization of the hippocampus and the lateral hypothalamusK99DA053388 · NIDA · PRINCETON UNIVERSITY · PI NIEH, HORNG-AN EDWARD · 2022 to 2023
$307kMechanisms underlying large-scale coordination of cortical activity during perceptual decisionsK99MH120047 · NIMH · PRINCETON UNIVERSITY · PI PINTO, LUCAS · 2019 to 2020
$217kCharacterization of Hippocampal Neural Activity in Evidence Accumulation and Decision-MakingF32MH119749 · NIMH · PRINCETON UNIVERSITY · PI NIEH, HORNG-AN EDWARD · 2019 to 2021
$192kNIDA NIH HHS K99 DA053388NIMH NIH HHS F32 MH119749NIMH NIH HHS K99 MH120047NINDS NIH HHS U01 NS090541NINDS NIH HHS U19 NS104648
Abstract
Hippocampal neurons encode physical variables
Indexed as
KnowledgeAnimalsCA1 Region, HippocampalCalciumDecision MakingFemaleHippocampusLearningMaleMiceModels, NeurologicalNeuronsCalcium
Identifiers
What OpenQuestion holds
Textmetadata
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.