Evidence map›Paper›PMID 34135447›Full record

ArticleScientific reports2021

A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma.

Giuseppe Giannaccare, Marco Pellegrini, Federico Bernabei, Lara Urbini, Fulvio Bergamini, Lorenzo Ferro Desideri, Alessandro Bagnis, Francesco Biagini, Paola Cassottana, Chiara Del Noce and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
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  8. Comparison of the efficacy and safety of ultrasonic cycloplastyInternational journal of ophthalmology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Giuseppe Giannaccare *Department of Ophthalmology, University Magna Graecia of Catanzaro, Viale Europa, 88100, Germaneto, Catanzaro, Italy. giuseppe.giannaccare@unicz.it.ORCID 0000-0003-2617-0289
Marco Pellegrini *Department of Ophthalmology, Ospedali Privati Forlì "Villa Igea", Forlì, Italy.
Federico BernabeiService d'ophtalmologie, Ophtalmopôle de Paris, Hospital Cochin, Paris, France.
Lara UrbiniDepartment of Ophthalmology, Scientific Institute Capitanio Hospital-IRCCS Foundation-Istituto Auxologico Italiano, Milan, Italy.
Fulvio BergaminiDepartment of Ophthalmology, Scientific Institute Capitanio Hospital-IRCCS Foundation-Istituto Auxologico Italiano, Milan, Italy.
Lorenzo Ferro DesideriEye Clinic, DiNOGMI, University of Genoa, Genoa, Italy.
Alessandro BagnisEye Clinic, DiNOGMI, University of Genoa, Genoa, Italy.
Francesco BiaginiEye Clinic, DiNOGMI, University of Genoa, Genoa, Italy.
Paola CassottanaEye Clinic, DiNOGMI, University of Genoa, Genoa, Italy.
Chiara Del NoceEye Clinic, DiNOGMI, University of Genoa, Genoa, Italy.
Adriano CarnevaliDepartment of Ophthalmology, University Magna Graecia of Catanzaro, Viale Europa, 88100, Germaneto, Catanzaro, Italy.
Vincenzo ScorciaDepartment of Ophthalmology, University Magna Graecia of Catanzaro, Viale Europa, 88100, Germaneto, Catanzaro, Italy.
Carlo E TraversoEye Clinic, DiNOGMI, University of Genoa, Genoa, Italy.
Aldo VaggeEye Clinic, DiNOGMI, University of Genoa, Genoa, Italy.
University of Genoa · ITMagna Graecia University · ITIRCCS Istituto Auxologico Italiano · ITGruppo Italiano per lo Studio dei Carcinomi dell’Apparato Digerente · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultrasound cyclo plasty (UCP) is a recently developed surgical technique for glaucoma allowing a selective and controlled coagulation of the ciliary body. We herein investigated the long-term efficacy and safety of UCP for the treatment of glaucoma. This prospective study included patients with primary and secondary glaucoma. All surgeries were performed using the EyeOP1 device (Eye Tech Care, Rillieux-la-Pape, France). Sixty-six patients were included, and 60 completed regularly the 2-year follow-up. Preoperative IOP was 28.5 ± 9.6 mmHg and significantly decreased to 17.0 ± 5.4 at 2 years (p < 0.001). The daily number of both hypotensive eye drops and acetazolamide tablets decreased significantly (respectively, from 2.6 ± 1.1 to 1.7 ± 1.2 and from 0.7 ± 0.8 to 0.2 ± 0.5; both p < 0.001). At 2 years, 68.1% of patients met the definition of qualified success (IOP < 21 mmHg regardless of glaucoma medications) and 10.3% of patients met the definition of complete success (IOP < 21 mmHg without glaucoma medications). No major intra- or postoperative complications occurred; however, 15 eyes required additional glaucoma surgery. These results suggest that UCP is an effective and safe procedure to reduce IOP in glaucoma patients through a 2-year follow-up period.

Indexed as

AgedAged, 80 and overFemaleFollow-Up StudiesGlaucomaHigh-Intensity Focused Ultrasound AblationHumansMaleMiddle AgedMulticenter Studies as TopicPostoperative ComplicationsProspective StudiesTreatment Outcome

Identifiers

PMID34135447
PMCPMC8209230
OpenAlexW3167847089

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.