Evidence map›Paper›PMID 34135404›Full record

ArticleScientific reports2021

Automated detection of cervical ossification of the posterior longitudinal ligament in plain lateral radiographs of the cervical spine using a convolutional neural network.

Masataka Miura, Satoshi Maki, Kousei Miura, Hiroshi Takahashi, Masayuki Miyagi, Gen Inoue, Kazuma Murata, Takamitsu Konishi, Takeo Furuya, Masao Koda and 4 more

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. IShuffleNet-PCNN hybrid classifier within an MResU-Net-based framework for spinal cord injury detection and classification using CT images.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  3. ShuffleLeNet architecture for spinal cord injury classification and level detection.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Masataka MiuraDepartment of Orthopaedic Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuou-ku, Chiba, 260-8670, Japan.
Satoshi MakiDepartment of Orthopaedic Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuou-ku, Chiba, 260-8670, Japan. satoshimaki@gmail.com.
Kousei MiuraDepartment of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Hiroshi TakahashiDepartment of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Masayuki MiyagiDepartment of Orthopaedic Surgery, Kitasato University School of Medicine, Sagamihara, Japan.
Gen InoueDepartment of Orthopaedic Surgery, Kitasato University School of Medicine, Sagamihara, Japan.
Kazuma MurataDepartment of Orthopedic Surgery, Tokyo Medical University, Tokyo, Japan.
Takamitsu KonishiDepartment of Orthopedic Surgery, Tokyo Medical University, Tokyo, Japan.
Takeo FuruyaDepartment of Orthopaedic Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuou-ku, Chiba, 260-8670, Japan.
Masao KodaDepartment of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Masashi TakasoDepartment of Orthopaedic Surgery, Kitasato University School of Medicine, Sagamihara, Japan.
Kenji EndoDepartment of Orthopedic Surgery, Tokyo Medical University, Tokyo, Japan.
Seiji OhtoriDepartment of Orthopaedic Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuou-ku, Chiba, 260-8670, Japan.
Masashi YamazakiDepartment of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Chiba University · JPUniversity of Tsukuba · JPKitasato University · JPTokyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical ossification of the posterior longitudinal ligament (OPLL) is a contributing factor to spinal cord injury or trauma-induced myelopathy in the elderly. To reduce the incidence of these traumas, it is essential to diagnose OPLL at an early stage and to educate patients how to prevent falls. We thus evaluated the ability of our convolutional neural network (CNN) to differentially diagnose cervical spondylosis and cervical OPLL. We enrolled 250 patients with cervical spondylosis, 250 patients with cervical OPLL, and 180 radiographically normal controls. We evaluated the ability of our CNN model to distinguish cervical spondylosis, cervical OPLL, and controls, and the diagnostic accuracy was compared to that of 5 board-certified spine surgeons. The accuracy, average recall, precision, and F1 score of the CNN for classification of lateral cervical spine radiographs were 0.86, 0.86, 0.87, and 0.87, respectively. The accuracy was higher for CNN compared to any expert spine surgeon, and was statistically equal to 4 of the 5 experts and significantly higher than that of 1 expert. We demonstrated that the performance of the CNN was equal or superior to that of spine surgeons.

Indexed as

Neural Networks, ComputerAgedCervical VertebraeDiagnosis, DifferentialFemaleHumansMaleOssification of Posterior Longitudinal LigamentRadiographySensitivity and SpecificitySpondylosis

Identifiers

PMID34135404
PMCPMC8208978
OpenAlexW3171710228

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.