Evidence map›Paper›PMID 34135372›Full record

ArticleScientific reports2021

Stress in obstructive sleep apnea.

Jasmine L Wong, Fernando Martinez, Andrea P Aguila, Amrita Pal, Ravi S Aysola, Luke A Henderson, Paul M Macey

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Unfolding the role of exercise in the management of sleep disorders.European journal of applied physiology · 2024
    Review
  8. Review
  9. Age matters: association between age and depression severity at the time of OSA diagnosis and PAP adherence in adult patients.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Mental Health Conditions According to Stress and Sleep Disorders.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Jasmine L WongUCLA School of Nursing, University of California at Los Angeles, 700 Tiverton Avenue, Los Angeles, CA, 90095, USA.
Fernando MartinezUCLA School of Nursing, University of California at Los Angeles, 700 Tiverton Avenue, Los Angeles, CA, 90095, USA.
Andrea P AguilaUCLA School of Nursing, University of California at Los Angeles, 700 Tiverton Avenue, Los Angeles, CA, 90095, USA.
Amrita PalUCLA School of Nursing, University of California at Los Angeles, 700 Tiverton Avenue, Los Angeles, CA, 90095, USA.
Ravi S AysolaDepartment of Medicine (Division of Pulmonary and Critical Care), David Geffen School of Medicine at UCLA, University of California at Los Angeles, Los Angeles, CA, 90095, USA.
Luke A HendersonDepartment of Anatomy and Histology, Sydney Medical School, University of Sydney, Sydney, Australia.
Paul M MaceyUCLA School of Nursing, University of California at Los Angeles, 700 Tiverton Avenue, Los Angeles, CA, 90095, USA. pmacey@ucla.edu.
University of California, Los Angeles · USUniversity of Sydney · AU

Funding

Sex-specific brain injury and symptoms in sleep apneaR56NR017435 · NINR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MACEY, PAUL M · 2018 to 2018
$300k
NINR NIH HHS NR017435NINR NIH HHS R56 NR017435
6 · The paper itself

Abstract

People with obstructive sleep apnea (OSA) often have psychological symptoms including depression and anxiety, which are commonly treated with anti-depression or anti-anxiety interventions. Psychological stress is a related symptom with different intervention targets that may also improve mental state, but this symptom is not well characterized in OSA. We therefore aimed to describe stress in relation to other psychological symptoms. We performed a prospective cross-sectional study of 103 people, 44 untreated OSA (mean ± s.d. age: 51.2 ± 13.9 years, female/male 13/31) and 57 healthy control participants (age: 46.3 ± 13.8 years, female/male 34/23). We measured stress (Perceived Stress Scale; PSS), excessive daytime sleepiness (Epworth Sleepiness Scale; ESS), depressive symptoms (Patient Health Questionnaire; PHQ-9), and anxiety symptoms (General Anxiety Disorder; GAD-7). We compared group means with independent samples t-tests and calculated correlations between variables. Mean symptom levels were higher in OSA than control, including PSS (mean ± s.d.: OSA = 15.3 ± 6.9, control = 11.4 ± 5.5; P = 0.002), GAD-7 (OSA = 4.8 ± 5.0, control = 2.1 ± 3.9; P = 0.02), PHQ-9 (OSA = 6.9 ± 6.1, control = 2.6 ± 3.8; P = 0.003) and ESS (OSA = 8.1 ± 5.3, control = 5.0 ± 3.3; P = 0.03). Similar OSA-vs-control differences appeared in males, but females only showed significant differences in PHQ-9 and ESS, not PSS or GAD-7. PSS correlated strongly with GAD-7 and PHQ-9 across groups (R = 0.62-0.89), and moderately with ESS. Perceived stress is high in OSA, and closely related to anxiety and depressive symptoms. The findings support testing stress reduction in OSA.

Indexed as

AdultAgedAnxietyCase-Control StudiesCross-Sectional StudiesDepressionDisorders of Excessive SomnolenceFemaleHumansMaleMiddle AgedProspective StudiesSleep Apnea, ObstructiveStress, PsychologicalSurveys and QuestionnairesYoung Adult

Identifiers

PMID34135372
PMCPMC8209037
OpenAlexW3168475359

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.