Evidence map›Paper›PMID 34135349›Full record

ArticleScientific reports2021

Relationship between Apgar scores and long-term cognitive outcomes in individuals with Down syndrome.

Laura Del Hoyo Soriano, Tracie C Rosser, Debra R Hamilton, Danielle J Harvey, Leonard Abbeduto, Stephanie L Sherman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laura Del Hoyo SorianoDepartment of Psychiatry and Behavioral Sciences, MIND Institute University of California Davis, Sacramento, CA, USA. ldelhoyo@ucdavis.edu.
Tracie C RosserDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.
Debra R HamiltonDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.
Danielle J HarveyDepartment of Psychiatry and Behavioral Sciences, MIND Institute University of California Davis, Sacramento, CA, USA.
Leonard AbbedutoDepartment of Psychiatry and Behavioral Sciences, MIND Institute University of California Davis, Sacramento, CA, USA.
Stephanie L ShermanDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.

Funding

WISCONSIN CENTER ON MENTAL RETARDATION: CORE SUPPORTP30HD003352 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIDSON, RICHARD J · 1985 to 2015
$25.2M
Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEONARD J. ABBEDUTO, Melissa Dawn Bauman · 2020 to 2026
$9.7M
Waisman Intellectual and Developmental Disabilities Research Center Down Syndrome RegistryU54HD090256 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI CHANG, QIANG · 2016 to 2020
$6.0M
National Institute of Health P30HD03352National Institute of Health U54HD090256NICHD NIH HHS P30 HD003352NICHD NIH HHS P50 HD103526NICHD NIH HHS U54 HD090256
6 · The paper itself

Abstract

This study examined the contribution of the Apgar score at 1 and 5 min after birth to later cognitive functioning in 168 individuals with Down syndrome who were between 6 and 25 years of age at time of cognitive testing. Our results showed that a lower Apgar score at 1 min was related to a worse performance in later cognitive measures of receptive vocabulary, verbal comprehension and production, visual memory and working memory. Results also showed that a lower Apgar score at 5 min was only related to worse later outcomes of verbal comprehension and production and auditory working memory. Our findings suggest a need for future studies investigating how specific perinatal events reflected in the Apgar score are linked to later cognitive functioning in individuals with Down syndrome.

Indexed as

Apgar ScoreCognitionAdolescentAdultChildComprehensionDown SyndromeFemaleHumansInfant, NewbornMaleMemoryNeuropsychological TestsVocabularyYoung Adult

Identifiers

PMID34135349
PMCPMC8208985

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.