Evidence map›Paper›PMID 34135285›Full record

ArticleCritical care medicine2021

Exhalation Spreading During Nasal High-Flow Therapy at Different Flow Rates.

Dominic Dellweg, Jens Kerl, Amayu Wakoya Gena, Hayder Alsaad, Conrad Voelker

Abstract read
In one paragraph

Article in Critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dominic DellwegDepartment for Pulmonary and Intensive Care Medicine, Kloster Grafschaft, Schmallenberg, Germany.
Jens KerlDepartment for Pulmonary and Intensive Care Medicine, Kloster Grafschaft, Schmallenberg, Germany.
Amayu Wakoya GenaDepartment of Building Physics, Bauhaus-University Weimar, Weimar, Germany.
Hayder AlsaadDepartment of Building Physics, Bauhaus-University Weimar, Weimar, Germany.
Conrad VoelkerDepartment of Building Physics, Bauhaus-University Weimar, Weimar, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesSevere acute respiratory syndrome coronavirus 2 is transmitted through aerosols and droplets. Nasal high-flow therapy could possibly increase the spreading of exhalates from patients. The aim of this study is to investigate whether nasal high-flow therapy affects the range of the expiratory plume compared with spontaneous breathing.

designInterventional experiment on single breaths of a healthy volunteer.

settingResearch laboratory at the Bauhaus-University Weimar. SUBJECTS: A male subject.

interventionsVideos and images from a schlieren optical system were analyzed during spontaneous breathing and different nasal high-flow rates. MEASUREMENTS AND MAIN

resultsThe maximal exhalation spread was 0.99, 2.18, 2.92, and 4.1 m during spontaneous breathing, nasal high-flow of 20 L/min, nasal high-flow of 40 L/min, and nasal high-flow of 60 L/min, respectively. Spreading of the expiratory plume in the sagittal plane can completely be blocked with a surgical mask.

conclusionsNasal high-flow therapy increases the range of the expiratory air up to more than 4 meters. The risk to pick up infectious particles could be increased within this range. Attachment of a surgical mask over the nasal high-flow cannula blocks the expiratory airstream.

Indexed as

CannulaExhalationPulmonary VentilationAdultDisease Transmission, InfectiousHealthy VolunteersHumansMaleMicroscopy, VideoOxygen Inhalation TherapyRespiratory RateTidal Volume

Identifiers

PMID34135285
PMCPMC8204857

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.