Evidence map›Paper›PMID 34135128›Full record

ArticleAging2021

Pan-cancer analysis reveals an immunological role and prognostic potential of PXN in human cancer.

Yun Chen, Han Zhao, Yan Xiao, Peijun Shen, Li Tan, Shaohui Zhang, Qiong Liu, Zhengrong Gao, Jie Zhao, Yaqiong Zhao and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

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  12. Pancancer Analysis of the Oncogenic and Prognostic Role ofInternational journal of molecular sciences · 2022
    Article
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  18. Identification ofGenes · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Yun ChenDepartment of Stomatology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Han ZhaoDepartment of Ophthalmology, Eye, Ear, Nose, and Throat Hospital of Fudan University, Shanghai 200000, China.
Yan XiaoNursing Department, Ganzhou Municipal Hospital, Gannan Medical University, Ganzhou, Jiangxi 341000, China.
Peijun ShenDepartment of Gastroenterology, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410011, China.
Li TanDepartment of Stomatology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Shaohui ZhangDepartment of Stomatology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Qiong LiuDepartment of Stomatology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Zhengrong GaoDepartment of Stomatology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Jie ZhaoDepartment of Stomatology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Yaqiong ZhaoDepartment of Stomatology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Yue GuoDepartment of Stomatology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Yunzhi FengDepartment of Stomatology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Central South University · CNSecond Xiangya Hospital of Central South University · CNFudan University · CNGannan Medical University · CNThird Xiangya Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paxillin (PXN) is a protein involved in numerous physiological processes, and its presence is closely related to the occurrence and development of many types of tumors. However, no studies have analyzed PXN from a pan-cancer perspective. We analyzed

Indexed as

Cancer-Associated FibroblastsGene Expression Regulation, NeoplasticHumansKaplan-Meier EstimateLymphocytes, Tumor-InfiltratingMutationNeoplasmsPaxillinPhosphorylationPrognosisSurvival AnalysisPaxillinPXN protein, humanimmune infiltrationpan-cancerPXNsurvivalTCGA

Identifiers

PMID34135128
PMCPMC8266322
OpenAlexW3167454644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.