Evidence map›Paper›PMID 34135064›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2021

MHC Class II Presentation Is Affected by Polymorphism in the

Emily Cullum, Austin M Graves, Vera L Tarakanova, Lisa K Denzin, Tatyana Golovkina

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A human gutScience (New York, N.Y.) · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Emily CullumCommittee on Immunology, University of Chicago, Chicago, IL.ORCID 0000-0002-6741-2574
Austin M GravesGraduate School of Biomedical Sciences, Rutgers, The State University of New Jersey, New Brunswick, NJ.ORCID 0000-0002-9891-6919
Vera L TarakanovaDepartment of Microbiology and Immunology, Cancer Center, Medical College of Wisconsin, Milwaukee, WI.
Lisa K DenzinDepartment of Microbiology and Immunology, Cancer Center, Medical College of Wisconsin, Milwaukee, WI.ORCID 0000-0002-0554-4547
Tatyana GolovkinaCommittee on Immunology, University of Chicago, Chicago, IL; tgolovki@bsd.uchicago.edu.ORCID 0000-0002-2924-6747
Rutgers, The State University of New Jersey · USUniversity of Chicago · USMedical College of Wisconsin · US

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI CHIEN-MIN KAO · 1985 to 2026
$122.1M
Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
New retroviral restriction factorR01AI117535 · NIAID · UNIVERSITY OF CHICAGO · PI GOLOVKINA, TATYANA V · 2016 to 2020
$3.2M
New retroviral restriction factorR56AI117535 · NIAID · UNIVERSITY OF CHICAGO · PI GOLOVKINA, TATYANA V · 2021 to 2021
$776k
NCATS NIH HHS UL1 TR000430NCI NIH HHS P30 CA014599NIAID NIH HHS R01 AI117535NIAID NIH HHS R56 AI117535
6 · The paper itself

Abstract

Pathogen-derived peptides are loaded on MHC class II (MHCII) and presented to CD4

Indexed as

AnimalsHistocompatibility Antigens Class IIImmunoglobulinsMiceMice, CongenicMice, Inbred C57BLMice, KnockoutPolymorphism, GeneticH-2O antigenHistocompatibility Antigens Class IIImmunoglobulins

Identifiers

PMID34135064
PMCPMC8674376
OpenAlexW3168366672

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.