Evidence map›Paper›PMID 34134988›Full record

ArticleScience advances2021

Diving beetle-like miniaturized plungers with reversible, rapid biofluid capturing for machine learning-based care of skin disease.

Sangyul Baik, Jihyun Lee, Eun Je Jeon, Bo-Yong Park, Da Wan Kim, Jin Ho Song, Heon Joon Lee, Seung Yeop Han, Seung-Woo Cho, Changhyun Pang

Abstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  11. Biomimetic Wearable Sensors: Emerging Combination of Intelligence and Electronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  12. Artificial Intelligence-Powered Electronic Skin.Nature machine intelligence · 2023
    Article
  13. Article
  14. Review
  15. Review
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  17. Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sangyul BaikSchool of Chemical Engineering, Sungkyunkwan University (SKKU), 2066 Seobu-ro, Jangan-gu, Suwon 16419, Republic of Korea.ORCID 0000-0003-0224-2161
Jihyun LeeSchool of Chemical Engineering, Sungkyunkwan University (SKKU), 2066 Seobu-ro, Jangan-gu, Suwon 16419, Republic of Korea.
Eun Je JeonDepartment of Biotechnology, Yonsei University, 50 Yonsei-ro, Seoul 03722, Republic of Korea.ORCID 0000-0003-4943-3520
Bo-Yong ParkMcConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec H3A 2B4, Canada.ORCID 0000-0001-7096-337X
Da Wan KimSchool of Chemical Engineering, Sungkyunkwan University (SKKU), 2066 Seobu-ro, Jangan-gu, Suwon 16419, Republic of Korea.
Jin Ho SongSchool of Chemical Engineering, Sungkyunkwan University (SKKU), 2066 Seobu-ro, Jangan-gu, Suwon 16419, Republic of Korea.
Heon Joon LeeSchool of Chemical Engineering, Sungkyunkwan University (SKKU), 2066 Seobu-ro, Jangan-gu, Suwon 16419, Republic of Korea.
Seung Yeop HanDepartment of Biotechnology, Yonsei University, 50 Yonsei-ro, Seoul 03722, Republic of Korea.ORCID 0000-0001-8837-4522
Seung-Woo ChoDepartment of Biotechnology, Yonsei University, 50 Yonsei-ro, Seoul 03722, Republic of Korea. seungwoocho@yonsei.ac.kr chpang@skku.edu.ORCID 0000-0001-8058-332X
Changhyun PangSchool of Chemical Engineering, Sungkyunkwan University (SKKU), 2066 Seobu-ro, Jangan-gu, Suwon 16419, Republic of Korea. seungwoocho@yonsei.ac.kr chpang@skku.edu.ORCID 0000-0001-8339-7880

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in bioinspired nano/microstructures have received attention as promising approaches with which to implement smart skin-interfacial devices for personalized health care. In situ skin diagnosis requires adaptable skin adherence and rapid capture of clinical biofluids. Here, we report a simple, all-in-one device consisting of microplungers and hydrogels that can rapidly capture biofluids and conformally attach to skin for stable, real-time monitoring of health. Inspired by the male diving beetle, the microplungers achieve repeatable, enhanced, and multidirectional adhesion to human skin in dry/wet environments, revealing the role of the cavities in these architectures. The hydrogels within the microplungers instantaneously absorb liquids from the epidermis for enhanced adhesiveness and reversibly change color for visual indication of skin pH levels. To realize advanced biomedical technologies for the diagnosis and treatment of skin, our suction-mediated device is integrated with a machine learning framework for accurate and automated colorimetric analysis of pH levels.

Indexed as

ColeopteraMachine LearningAdhesivenessAnimalsHydrogelsMaleSkin DiseasesHydrogels

Identifiers

PMID34134988
PMCPMC8208721

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.