Evidence map›Paper›PMID 34134985›Full record

ArticleScience advances2021

Toward the use of neural networks for influenza prediction at multiple spatial resolutions.

Emily L Aiken, Andre T Nguyen, Cecile Viboud, Mauricio Santillana

Abstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
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  6. Ensemble approaches for short-term dengue fever forecasts: A global evaluation study.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  10. Review
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  14. Psychological AI: Designing Algorithms Informed by Human Psychology.Perspectives on psychological science : a journal of the Association for Psychological Science · 2024
    Article
  15. Article
  16. Spatial analysis and risk mapping ofParasite epidemiology and control · 2023
    Article
  17. Article
  18. Graph Neural Network Modeling of Web Search Activity for Real-time Pandemic Forecasting.Proceedings. IEEE International Conference on Healthcare Informatics · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emily L AikenSchool of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA. emilyaiken@berkeley.edu msantill@fas.harvard.edu.ORCID http://orcid.org/0000-0003-4374-3536
Andre T NguyenBooz Allen Hamilton, Columbia, MD 21044, USA.ORCID http://orcid.org/0000-0001-7131-6879
Cecile ViboudFogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA.ORCID http://orcid.org/0000-0003-3243-4711
Mauricio SantillanaSchool of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA. emilyaiken@berkeley.edu msantill@fas.harvard.edu.ORCID http://orcid.org/0000-0002-4206-418X

Funding

Development of an Open-Source and Data-Driven Modeling Platform to Monitor and Forecast Disease ActivityR01GM130668 · NIGMS · NORTHEASTERN UNIVERSITY · PI SANTILLANA, MAURICIO · 2018 to 2022
$1.9M
NIGMS NIH HHS R01 GM130668
6 · The paper itself

Abstract

Mitigating the effects of disease outbreaks with timely and effective interventions requires accurate real-time surveillance and forecasting of disease activity, but traditional health care-based surveillance systems are limited by inherent reporting delays. Machine learning methods have the potential to fill this temporal "data gap," but work to date in this area has focused on relatively simple methods and coarse geographic resolutions (state level and above). We evaluate the predictive performance of a gated recurrent unit neural network approach in comparison with baseline machine learning methods for estimating influenza activity in the United States at the state and city levels and experiment with the inclusion of real-time Internet search data. We find that the neural network approach improves upon baseline models for long time horizons of prediction but is not improved by real-time internet search data. We conduct a thorough analysis of feature importances in all considered models for interpretability purposes.

Identifiers

PMID34134985
PMCPMC8208709

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.