Evidence map›Paper›PMID 34134917›Full record

Observational studyClinical nutrition (Edinburgh, Scotland)2022

Impact of nutritional therapy during the first wave of the COVID-19 pandemic in intensive care patients: A retrospective observational study.

Aude de Watteville, Florencia Montalbano, Hannah Wozniak, Tinh-Hai Collet, Cyril Jaksic, Christophe Le Terrier, Jérôme Pugin, Laurence Genton, Claudia Paula Heidegger

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Clinical nutrition (Edinburgh, Scotland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Aude de WattevilleClinical Nutrition, Division of Endocrinology, Diabetes, Nutrition and Therapeutic Education, Department of Medicine and the University of Geneva Faculty of Medicine Geneva, Switzerland; Division of Intensive Care, Department of Acute Medicine, Geneva University Hospitals and the University of Geneva Faculty of Medicine Geneva, Switzerland.
Florencia MontalbanoDivision of Intensive Care, Department of Acute Medicine, Geneva University Hospitals and the University of Geneva Faculty of Medicine Geneva, Switzerland.
Hannah WozniakDivision of Intensive Care, Department of Acute Medicine, Geneva University Hospitals and the University of Geneva Faculty of Medicine Geneva, Switzerland.
Tinh-Hai ColletClinical Nutrition, Division of Endocrinology, Diabetes, Nutrition and Therapeutic Education, Department of Medicine and the University of Geneva Faculty of Medicine Geneva, Switzerland.
Cyril JaksicCRC & Division of Clinical-Epidemiology, Department of Health and Community Medicine, University of Geneva & University Hospitals of Geneva, Switzerland.
Christophe Le TerrierDivision of Intensive Care, Department of Acute Medicine, Geneva University Hospitals and the University of Geneva Faculty of Medicine Geneva, Switzerland.
Jérôme PuginDivision of Intensive Care, Department of Acute Medicine, Geneva University Hospitals and the University of Geneva Faculty of Medicine Geneva, Switzerland.
Laurence GentonClinical Nutrition, Division of Endocrinology, Diabetes, Nutrition and Therapeutic Education, Department of Medicine and the University of Geneva Faculty of Medicine Geneva, Switzerland.
Claudia Paula HeideggerDivision of Intensive Care, Department of Acute Medicine, Geneva University Hospitals and the University of Geneva Faculty of Medicine Geneva, Switzerland. Electronic address: claudia-paula.heidegger@hcuge.ch.
University of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND &

aimsThe COVID-19 pandemic has caused major organizational challenges to healthcare systems concerning staff, material and bed availability. Nutrition was not a priority in the intensive care unit (ICU) at the beginning of the pandemic with the need for simplified protocols. We aimed to assess the impact of a simplified nutritional protocol for critically ill COVID-19 patients during the pandemic first wave.

methodsWe included all patients with SARS-CoV-2 infections, admitted to the ICU of the Geneva University Hospitals for at least 4 days from March 9 to May 19, 2020. Data on the route and solution of nutritional therapy, prescribed and received volume, calorie and protein intake, amount of insulin, propofol and glucose administered were collected daily during the entire ICU stay. We compared nutritional outcomes between patients admitted to the ICU before and after implementing the simplified nutritional protocol using unpaired t-test.

resultsOut of 119 patients, 48 were hospitalized in the ICU before, 47 across and 24 after the implementation of the nutritional protocol. The mean age was 63.2 (±12.7) years and 76% were men without significant difference between before and after group. The nutritional protocol implementation led to an increase in caloric intake (1070 vs. 1357 kcal/day, p = 0.018) and in the percentage of days within 80-100% of the energy target (11 vs. 20%, p = 0.021). The protein debt decreased significantly from 48 g/day to 37 g/day (p = 0.015). No significant difference in the percentage of days within the protein target (80-100%) was observed.

conclusionsCalorie and protein coverage improved after the implementation of the simplified nutritional protocol in critically ill COVID-19 patients. Further studies are needed to assess the impact of such an approach on patients' clinical outcomes.

Indexed as

COVID-19AgedCritical CareCritical IllnessFemaleHumansIntensive Care UnitsMaleMiddle AgedPandemicsSARS-CoV-2COVID-19ICUNutrition protocolNutrition therapyPandemicSARS-CoV-2

Identifiers

PMID34134917
PMCPMC8176891
OpenAlexW3170742922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.