Evidence map›Paper›PMID 34134876›Full record

ReviewJournal of substance abuse treatment2021

Validity and item response theory properties of the Alcohol Use Disorders Identification Test for primary care alcohol use screening in Mozambique (AUDIT-MZ).

Dana L Atkins, Vasco F J Cumbe, Alberto Muanido, Nelia Manaca, Hélder Fumo, Pedro Chiruca, Leecreesha Hicks, Bradley H Wagenaar

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of substance abuse treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05925270 (Substituting SMSs for Provider-delivered Care to Improve Alcohol Use Outcomes in People With and Without HIV in Lesotho), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05925270 nacompletednot on this mapstarted 2023, after this paper: background citation

Substituting SMSs for Provider-delivered Care to Improve Alcohol Use Outcomes in People With and Without HIV in Lesotho

TypeinterventionalSponsorUniversity Hospital, Basel, SwitzerlandRan2023 to 2025Enrolled255ConditionsAlcohol Use Disorder, Mild, Alcohol Use Disorder, ModerateArmsmhGAP-Remote, mhGAP-Standard
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dana L AtkinsDepartment of Global Health, University of Washington, Seattle, WA, USA. Electronic address: dlatkins@uw.edu.
Vasco F J CumbeSofala Provincial Health Directorate, Department of Mental Health, Ministry of Health, Beira, Mozambique; Faculdade de Medicina, Universidade Eduardo Mondlane, Mozambique; Escola Paulista de Medicina, Universidade Federal de São Paulo, Departamento de Psiquiatria, Brazil. Electronic address: vcumbe@gmail.com.
Alberto MuanidoHealth Alliance International, Beira, Mozambique. Electronic address: muanido@gmail.com.
Nelia ManacaHealth Alliance International, Beira, Mozambique.
Hélder FumoSofala Provincial Health Directorate, Department of Mental Health, Ministry of Health, Beira, Mozambique.
Pedro ChirucaSofala Provincial Health Directorate, Department of Mental Health, Ministry of Health, Beira, Mozambique.
Leecreesha HicksHealth Alliance International, Beira, Mozambique.
Bradley H WagenaarDepartment of Global Health, University of Washington, Seattle, WA, USA; Health Alliance International, Seattle, WA, USA; Department of Epidemiology, University of Washington, Seattle, WA, USA.

Funding

Strengthening the identification and treatment of depression in primary care in MozambiqueK01MH110599 · NIMH · UNIVERSITY OF WASHINGTON · PI WAGENAAR, BRADLEY · 2017 to 2020
$633k
NIMH NIH HHS K01 MH110599
6 · The paper itself

Abstract

backgroundNo validated tools exist to screen for substance use or dependence in Mozambique. The aim of this study was to validate the Alcohol Use Disorder Identification Test (AUDIT) for use in primary care settings in Mozambique.

methodsThe study administered a final adapted Mozambican 10-item AUDIT (AUDIT-10-MZ) to 502 individuals from antenatal, postpartum, and general outpatient consultations in three Ministry of Health primary health care clinics in Sofala Province, Mozambique. The study evaluated the AUDIT-10-MZ against the MINI 5.0-MZ as a gold standard diagnostic tool.

resultsUsing the MINI 5.0-MZ, 16 (3.2%) of the sample tested positive for alcohol dependence and 3 (0.6%) tested positive for harmful alcohol use. The full AUDIT-10-MZ had acceptable internal consistency (α = 0.74); however, the shorter AUDIT-C-MZ had a higher alpha value than the full AUDIT screener (α = 0.79). The AUDIT-10-MZ performed well for screening in primary care, achieving areas under the receiver operating characteristic curves (AUROCs) of 0.94 (95% CI: 0.91, 0.96) for alcohol dependence. The AUDIT-C-MZ also performed well with an AUROC of 0.88 (95% CI: 0.80, 0.96) for alcohol dependence. Using a cut-off of ≥6, the AUDIT-10-MZ achieved a sensitivity of 68.8% and specificity of 92.0% for screening for alcohol dependence; a cut-off of ≥3 for the AUDIT-C-MZ achieved a sensitivity of 56.3% and specificity of 90.7%.

conclusionsBoth the AUDIT-10-MZ and AUDIT-C-MZ are valid instruments for screening for alcohol dependence in Mozambique. The AUDIT-C-MZ performed particularly well and providers could use it as a brief screener in primary care settings. Optimal cut-points will depend on weighing false positives and false negatives but could be employed at ≥ 6 or ≥ 7 for the AUDIT-10-MZ and at ≥ 2 or ≥ 3 for the AUDIT-C-MZ. Future implementation research is needed to examine how best to integrate screening for substance use or dependence in primary care settings in Mozambique and other similar LMICs.

Indexed as

AlcoholismFemaleHumansMass ScreeningMozambiquePregnancyPrimary Health CareReproducibility of ResultsSurveys and QuestionnairesAlcohol misuse screening toolAlcohol useAUDITMozambiquePrimary health careValidation

Identifiers

PMID34134876
PMCPMC8217722

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.