Evidence map›Paper›PMID 34134763›Full record

ArticleEuropean journal of medical research2021

Investigation of antibiotic susceptibilities of Brucella Strains isolated from various clinical samples in eastern Turkey.

Esra Gültekin, Muhammet Hamidullah Uyanık, Ayşe Albayrak, Selçuk Kılıç

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in European journal of medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Prevalence of Brucella melitensis and Brucella abortus aminoglycoside-resistant isolates: a systematic review and meta-analysis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Pooled it
  4. Analysis of Bacteremic Brucellosis Caused byInfectious diseases & clinical microbiology · 2026
    Article
  5. Frontiers in cellular and infection microbiology · 2025
    Article
  6. Whole-Genome Sequencing of Brucella melitensis Isolates from Kuwait for the Identification of Biovars, Variants, and Relationship within a Biovar.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2025
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Esra GültekinDepartment of Medical Microbiology, Faculty of Medicine, Erzincan Binali Yıldırım University, Erzincan, 24100, Turkey. esra_gltkn83@hotmail.com.ORCID http://orcid.org/0000-0002-8457-3564
Muhammet Hamidullah UyanıkDepartment of Medical Microbiology, Atatürk University Faculty of Medicine, Erzurum, 25240, Turkey.
Ayşe AlbayrakDepartment of Infectious Diseases and Clinical Microbiology, Atatürk University Faculty of Medicine, Erzurum, 25240, Turkey.
Selçuk KılıçDepartment of Microbiology Reference Laboratories and Biological Products, General Directorate of Public Health, Ankara, 06100, Turkey.
Atatürk University · TRErzincan Binali Yıldırım University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBrucellosis is a worldwide zoonotic disease that causes serious public health problems. This study aimed to identify Brucella strains isolated from various clinical samples by conventional and molecular methods and to determine antimicrobial susceptibilities against doxycycline (DOX), streptomycin (STR), ciprofloxacin (CIP) and rifampicin (RIF) by the gradient strip (E test) test method.

methodsA total of 87 Brucella strains isolated from various clinical specimens between 2004 and 2018 were included in this study. While four of the 87 strains included in the study were identified only at the genus level, the remaining 83 strains were identified at the species level by the Real-Time Multiplex PCR (M-RT-PCR) method and conventional methods were used for biotyping.

resultsAccording to molecular identification results, 83 strains were identified as B. melitensis by the M-RT-PCR method, with 82 strains identified as Brucella melitensis biovar (bv) 3 and one as B. melitensis bv 1 according to the conventional biotyping method. Among the antibiotics studied, CIP was found to be the most active agent according to the minimum inhibitory concentrations (MIC)

conclusionsIn our study, all strains were identified as B. melitensis. DOX, STR, CIP and RIF used in the treatment of brucellosis were found to be effective.

Indexed as

Anti-Bacterial AgentsBrucellaBrucellosisDNA, BacterialFemaleHumansMaleMicrobial Sensitivity TestsRetrospective StudiesTurkeyAnti-Bacterial AgentsDNA, BacterialAntimicrobial susceptibilitiesBiotypingBrucellaE test

Identifiers

PMID34134763
PMCPMC8207786
OpenAlexW3166542724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.