SynthesisBMC musculoskeletal disorders2021
Surgical treatment of benign osteolytic lesions in the femoral head and neck: a systematic review.
Synthesis in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- A case of a pathological fracture in the femoral neck due to chondroblastoma: 10-year follow-up without recurrence after curettage and bone grafting.Journal of surgical case reports · 2026Article
- A modified surgical strategy for proximal femur benign tumors: a retrospective analysis of 100 patients.BMC musculoskeletal disorders · 2026Article
- Combined Approach (Surgery + Systemic Adjuvant Therapy) in a Giant Cell Tumor of Proximal Femur: A Rare Case Report.Journal of orthopaedic case reports · 2026Article
- Chondroblastoma of the femoral head:current and future therapeutic options.Journal of bone oncology · 2025Review
- Trapdoor Procedure for Benign Bone Lesions in the Femoral Head of Skeletally Immature Children.Orthopaedic surgery · 2025Article
- Giant Cell Tumor of the Proximal Femur with Pathological Fracture of Femoral neck.Journal of orthopaedic case reports · 2025Article
- Case Report: Trapdoor procedure combined with arthrodiastasis treating chondroblastoma of the femoral head in adolescents.Frontiers in pediatrics · 2025Article
- Chondroblastoma of the femoral head: curettage without dislocation.BMC surgery · 2024Article
- Disappearance of femoral head shortly after femoral neck fracture: a case report and literature review.The Journal of international medical research · 2024Review
- Two Cannulated Screws Provide Sufficient Biomechanical Strength for Prophylactic Fixation in Adult Patients With an Aggressive Benign Femoral Neck Lesion.Frontiers in bioengineering and biotechnology · 2022Article
- Comparative Analysis of Two Surgical Treatment Options for Giant Cell Tumor of the Proximal Femur: Extended Curettage and Segmental Resection.Frontiers in oncology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesTreatment of benign osteolytic lesions in the femoral head and neck can be extremely challenging, particularly in children with open physis or for aggressive tumors with pathological fracture. There remains the difficult management decision as to whether to perform complete excision of the involved area or only curettage. Moreover, there is no agreed consensus on the optimal approach to lesion access when performing curettage, which included the transcervical, open and direct approach. The current systematic review aims to provide guidance for selection of surgical methods in clinical practice by comparing the advantages and drawbacks of different procedures.
methodsA comprehensive literature search of PubMed, Embase and Web of Science databases were executed for human studies restricted to the English language. The search was filtered to include studies published from January 1980 to January 2020.
resultsA total of 33 articles including 274 patients were enrolled in the final analysis. The most common diagnosis was chondroblastoma (CBT) (104, 38.0%), followed by giant cell tumor (GCT) (56, 20.4%). There were 57 (20.8%) patients with pathological fracture. Intralesional curettage was performed in 257 (93.8%) patients with the local recurrence of 12.5% at the mean follow-up of 51.5 months. The patients who were presented with open physis or curetted via transcervical approach developed higher local recurrence in patients with CBT (P < 0.001). The local recurrence rate of GCT is 33.3% after curettage, while 8 of 9 (88.9%) patients with fracture were treated successfully with joint preservation. Two of 45 (4.4%) patients developed avascular necrosis (AVN) of femoral head after surgical hip dislocation. The reported Musculoskeletal Tumor Society (MSTS) Score was comparable among patients with different approaches to curettage.
conclusionThe majority of benign osteolytic lesions in the femoral head and neck can be treated with intralesional curettage with acceptable local tumor control and satisfactory function. The incidence of local recurrence might be decreased dramatically for lesion access under direct visualization. The native joint maintenance could be achieved even in patients with aggressive lesions presenting pathological fracture.
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