ArticleBMC biotechnology2021
Development of a method for phycocyanin recovery from filamentous cyanobacteria and evaluation of its stability and antioxidant capacity.
Article in BMC biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 58 citations in OpenAlex.
- Topical C-Phycocyanin-Loaded Transfersomes Attenuate Early Proinflammatory Epidermal Remodelling in a DMBA/TPA-Induced Mouse Model of Skin Dysplasia.Pharmaceutics · 2026Article
- Carbon source-mediated metabolic and bioprocess optimization for C-phycocyanin enrichment in Phormidium sp. A02 under two-phase static mixotrophic culture.Bioprocess and biosystems engineering · 2026Article
- Response surface methodology-based approach for enhanced C-Phycocyanin production from3 Biotech · 2025Article
- Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria.FEBS open bio · 2025Article
- Phycobilins Versatile Pigments with Wide-Ranging Applications: Exploring Their Uses, Biological Activities, Extraction Methods and Future Perspectives.Marine drugs · 2025Review
- Unraveling the unique bioactivities of highly purified C-phycocyanin and allophycocyanin.Journal of biological engineering · 2025Article
- Recent progress in the cyanobacterial products and applications of phycocyanins.World journal of microbiology & biotechnology · 2025Review
- Phycocyanin extraction fromCurrent research in food science · 2025Review
- Optimizing Phycocyanin Extraction from Cyanobacterial Biomass: A Comparative Study of Freeze-Thaw Cycling with Various Solvents.Marine drugs · 2024Article
- A new and promising C-phycocyanin-producing cyanobacterial strain,Frontiers in microbiology · 2024Article
- Coproduction of lipids and carotenoids by the novel green algaBiotechnology reports (Amsterdam, Netherlands) · 2023Article
- An extensive review of marine pigments: sources, biotechnological applications, and sustainability.Aquatic sciences · 2023Review
- Comparative Study of the Efficiency of Additives in the Extraction of Phycocyanin-C from Arthrospira maxima Using UltrasonicationMolecules (Basel, Switzerland) · 2022Article
- Improvement in the Sequential Extraction of Phycobiliproteins fromLife (Basel, Switzerland) · 2022Article
- The Antioxidant Activity of a Commercial and a Fractionated Phycocyanin on Human Skin Cells In Vitro.Molecules (Basel, Switzerland) · 2022Article
- Physicochemical degradation of phycocyanin and means to improve its stability: A short review.Journal of pharmaceutical analysis · 2022Review
- Cyano-Phycocyanin: Mechanisms of Action on Human Skin and Future Perspectives in Medicine.Plants (Basel, Switzerland) · 2022Review
- Commercial Potential of the CyanobacteriumBiology · 2022Article
- Preparation, Characterization, and Antioxidant Properties of Phycocyanin Complexes Based on Sodium Alginate and Lysozyme.Frontiers in nutrition · 2022Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMost commercial phycocyanins are extracted from a filamentous cyanobacterium, Arthrospira (Spirulina) platensis. Owing to the expenses of culture and complexities of the physical and chemical methods of phycocyanin purification, a more effective and simple method is required.
resultsWe developed a new method for efficiently recovering the blue pigment protein, phycocyanin, from unique filamentous cyanobacteria, Pseudanabaena sp. ABRG5-3 and Limnothrix sp. SK1-2-1. The cells were cultivated in economy medium BG11 and lysed by adding water in a 1:16 ratio of wet cells to water. After extraction and purification, 28-30% dry cell weight of phycocyanin was obtained and its purity was confirmed. The stabilities of the phycocyanins at different pH in the presence of high temperature and light conditions and their antioxidant abilities were assessed. Results indicated that the phycocyanins were stable and possessed antioxidant properties. Interestingly, the Pseudanabaena phycocyanin was less likely to deteriorate under acidic conditions.
conclusionsOverall, we developed a promising and novel method for producing high functional phycocyanin concentrations at a low cost. The possibilities of adapting this new phycocyanin biorefinery to unique bioreactor utilization have also been discussed.
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