Evidence map›Paper›PMID 34134145›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2022

Risk of Symptomatic Infection During a Second Coronavirus Disease 2019 Wave in Severe Acute Respiratory Syndrome Coronavirus 2-Seropositive Individuals.

Mattia Manica, Serena Pancheri, Piero Poletti, Giulia Giovanazzi, Giorgio Guzzetta, Filippo Trentini, Valentina Marziano, Marco Ajelli, Maria Grazia Zuccali, Pier Paolo Benetollo and 2 more

Abstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mattia ManicaCenter for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.
Serena PancheriDepartment of Prevention, Azienda Provinciale per i Servizi Sanitari, Trento, Italy.
Piero PolettiCenter for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.
Giulia GiovanazziDepartment of Prevention, Azienda Provinciale per i Servizi Sanitari, Trento, Italy.
Giorgio GuzzettaCenter for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.
Filippo TrentiniCenter for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.
Valentina MarzianoCenter for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.
Marco AjelliDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health, Bloomington, Indiana, USA.
Maria Grazia ZuccaliDepartment of Prevention, Azienda Provinciale per i Servizi Sanitari, Trento, Italy.
Pier Paolo BenetolloDepartment of Prevention, Azienda Provinciale per i Servizi Sanitari, Trento, Italy.
Stefano MerlerCenter for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.
Antonio FerroDepartment of Prevention, Azienda Provinciale per i Servizi Sanitari, Trento, Italy.

Funding

European Commission H2020-874850Istituto Superiore di Sanità Committee Ethics
6 · The paper itself

Abstract

We analyzed 221 coronavirus disease 2019 cases identified between June 2020 and January 2021 in 6074 individuals screened for immunoglobulin G antibodies in May 2020, representing 77% of residents of 5 Italian municipalities. The relative risk of developing symptomatic infection in seropositive participants was 0.055 (95% confidence interval, .014-.220).

Indexed as

COVID-19SARS-CoV-2Antibodies, ViralHumansImmunoglobulin GReinfectionAntibodies, ViralImmunoglobulin GCOVID-19natural immunityreinfection riskSARS-CoV-2serological screening

Identifiers

PMID34134145
PMCPMC8406865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.