Evidence map›Paper›PMID 34133976›Full record

ArticleThe ocular surface2021

Impact of the COVID-19 pandemic on eye strain and dry eye symptoms.

Ian J Saldanha, Rebecca Petris, Matthew Makara, Prabjot Channa, Esen K Akpek

Open access · greenAbstract read
In one paragraph

Article in The ocular surface, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Oral Intake ofBiomedicines · 2025
    Article
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  10. Article
  11. Article
  12. Article
  13. Covid-19 and its relation to the human eye: transmission, infection, and ocular manifestations.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Review
  14. An Online Questionnaire-Based Survey of 1076 Individuals in Poland to Identify the Prevalence of Ophthalmic Symptoms in Autumn 2022.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  15. Article
  16. Article
  17. Hydrogel-Based Biosensors.Gels (Basel, Switzerland) · 2022
    Review
  18. Article
  19. Article
  20. Sleep Loss Causes Dysfunction in Murine Extraorbital Lacrimal Glands.Investigative ophthalmology & visual science · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Ian J SaldanhaCenter for Evidence Synthesis in Health, Department of Health Services, Policy and Practice (Primary), Department of Epidemiology (Secondary), Brown University School of Public Health, Providence, RI, USA. Electronic address: ian_saldanha@brown.edu.
Rebecca PetrisDry Eye Foundation Poulsbo, Washington, USA. Electronic address: rebecca@dryeyefoundation.org.
Matthew MakaraDirector of Research and Scientific Affairs, Sjögren's Foundation Reston, Virginia, USA. Electronic address: mmakara@sjogrens.org.
Prabjot ChannaDepartment of Ophthalmology, Brown University Warren Alpert Medical School, Providence, RI, USA. Electronic address: pchanna@lifespan.org.
Esen K AkpekOcular Surface Disease Clinic, The Wilmer Eye Institute, Johns Hopkins University School of Medicine Baltimore, Maryland, USA. Electronic address: esakpek@jhmi.edu.
Brown University · USInouye Eye Hospital · JPJohns Hopkins University · USRome Foundation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAmong adult individuals with dry eye, assess the self-reported impact of the COVID-19 pandemic on (1) dry eye-related visual function, (2) reading efficiency, and (3) dry eye treatments used.

methodsIn June-July 2020, we conducted an online survey of adults with dry eye who spent at least somewhat more time at home during the pandemic than before. Consistent with TFOS DEWS II guidelines, we categorized respondents into mild, moderate, or severe dry eye based on treatment usage.

resultsWe included 388 respondents: 97 respondents (25%) with mild, 80 (21%) with moderate, and 211 (54%) with severe dry eye. In all three groups, screen/reading time generally doubled during the pandemic. Reduced work-related efficiency was noted by a considerable proportion of respondents (moderate dry eye: 51%, mild: 39%, and severe: 38%). Compared with respondents with mild dry eye, respondents with moderate dry eye were considerably more likely to note worsening symptoms: eye pain (OR = 2.57, 95% CI 1.22-5.41), headache from eye symptoms (OR = 2.34, 95% CI 1.11-4.90), and difficulty concentrating because of eye symptoms (OR = 2.79, 95% CI 1.37-5.66). Respondents with moderate dry eye with Sjögren's syndrome were most likely to note these. Respondents with severe dry eye were more likely than respondents with mild dry eye to report losing access to dry eye-related treatments (OR = 2.62, 95% CI 1.36-5.03).

conclusionsThe COVID-19 pandemic-related eye strain may be impacting symptoms, performance, and ultimately employment, especially for those with moderate dry eye. This may be compounding the already-high dry eye-related societal burden.

Indexed as

COVID-19Dry Eye SyndromesAdultHumansPandemicsSARS-CoV-2Surveys and QuestionnairesCOVID-19Dry eyeEye strainReadingVisual function

Identifiers

PMID34133976
PMCPMC8462938
OpenAlexW3169579877

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.