Evidence map›Paper›PMID 34133898›Full record

ArticleJournal of virology2021

Herpes Simplex Virus 1 UL34 Mutants That Affect Membrane Budding Regulation and Nuclear Lamina Disruption.

Amber Vu, Shaowen White, Tiffany Cassmann, Richard J Roller

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amber VuDepartment of Pediatrics, Carver College of Medicine, University of Iowagrid.214572.7, Iowa City, Iowa, USA.
Shaowen WhiteDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowagrid.214572.7, Iowa City, Iowa, USA.
Tiffany CassmannDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowagrid.214572.7, Iowa City, Iowa, USA.
Richard J RollerDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowagrid.214572.7, Iowa City, Iowa, USA.
University of Iowa · US

Funding

RESEARCH TRAINING IN INFECTIOUS DISEASEST32AI007343 · NIAID · UNIVERSITY OF IOWA · PI STAPLETON, JACK T. · 1988 to 2024
$5.0M
Training in Molecular Virology, Viral Pathogenesis and Viral VectorsT32AI007533 · NIAID · UNIVERSITY OF IOWA · PI Stanley Perlman · 1998 to 2026
$2.5M
Mechanism and regulation of protein kinase functions in HSV nuclear egressR21AI148831 · NIAID · UNIVERSITY OF IOWA · PI ROLLER, RICHARD J · 2020 to 2021
$425k
Regulation of budding during herpesvirus nuclear egressR21AI133155 · NIAID · UNIVERSITY OF IOWA · PI ROLLER, RICHARD J · 2017 to 2018
$419k
BLRD VA I01 BX000207NIAID NIH HHS R21 AI133155NIAID NIH HHS R21 AI148831NIAID NIH HHS T32 AI007343NIAID NIH HHS T32 AI007533
6 · The paper itself

Abstract

Nuclear envelope budding in herpesvirus nuclear egress may be negatively regulated, since the pUL31/pUL34 nuclear egress complex heterodimer can induce membrane budding without capsids when expressed ectopically or on artificial membranes

Indexed as

MutationVirus ReplicationActive Transport, Cell NucleusAnimalsChlorocebus aethiopsHerpes SimplexHerpesvirus 1, HumanHumansLamin Type ANuclear EnvelopeNuclear LaminaVero CellsViral ProteinsVirus ReleaseLamin Type AUL34 protein, Human herpesvirus 1Viral Proteinsherpes simplexmembrane buddingnuclear egressnuclear laminaprotein kinases

Identifiers

PMID34133898
PMCPMC8354240
OpenAlexW3166739888

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.